DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7646 and usp32

DIOPT Version :9

Sequence 1:	NP_001287124.1	Gene:	CG7646 / 40187	FlyBaseID:	FBgn0036926	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	XP_686236.6	Gene:	usp32 / 557981	ZFINID:	ZDB-GENE-100210-5	Length:	1585	Species:	Danio rerio

Alignment Length:	179	Identity:	45/179 - (25%)
Similarity:	76/179 - (42%)	Gaps:	26/179 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EDMEFLKTHTRYDEATIKEWYKGFKQDCPNGRLTPAKFVDMYKMFFPSGNAEEFCDHVFRTFDMD 77
            |:.:.:....||       |.  .|.....||.....||.:..   |..:| ...:.:|..||.:
Zfish   192 EESDIIDLEKRY-------WL--LKAQSRTGRFDLETFVPLVS---PPIHA-SLSEGLFHAFDEN 243

  Fly    78 KNGYIDFKEFLLAIDVTSSGTPEEKLKWAFRMYDVDGNGVIDIQEMTKIVQAIYDMLGACSSNRP 142
            ::.:|||||....:.....|...|:.|:.|:::|||.:||:...|:.::|.|   :|.....||.
Zfish   244 RDNHIDFKEISCGLSACCRGPVAERQKFCFKVFDVDRDGVLSRDEIHEMVVA---LLEVWKDNRT 305

  Fly   143 ------ADSAEERAKNIFAKMDENNDGQLTQDEF----LKGCLQDEELS 181
                  ..|..|..::|....|....|.||.:::    :|..|.:|.|:
Zfish   306 DTLPEFDSSVSEIVEDILKMHDTTKQGHLTLEDYQIWSVKSALANEFLN 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7646	NP_001287124.1	FRQ1	18..178	CDD:227455	42/169 (25%)
usp32	XP_686236.6	EF-hand_7	236..293	CDD:290234	18/56 (32%)
		EFh	237..293	CDD:238008	18/55 (33%)
		EF-hand_7	270..342	CDD:290234	20/74 (27%)
		EFh	270..338	CDD:298682	20/70 (29%)
		DUSP	<519..586	CDD:283896
		UBP12	521..1546	CDD:227847
		Ubiquitin_3	623..710	CDD:291502
		Peptidase_C19	733..>918	CDD:271592
		Peptidase_C19	<1220..1546	CDD:271592
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900