DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7646 and ncs1

DIOPT Version :9

Sequence 1:	NP_001287124.1	Gene:	CG7646 / 40187	FlyBaseID:	FBgn0036926	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_592879.1	Gene:	ncs1 / 2542523	PomBaseID:	SPAC18B11.04	Length:	190	Species:	Schizosaccharomyces pombe

Alignment Length:	186	Identity:	84/186 - (45%)
Similarity:	122/186 - (65%)	Gaps:	3/186 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCLSSKDRLTKEDMEFLKTHTRYDEATIKEWYKGFKQDCPNGRLTPAKFVDMYKMFFPSGNAEE 65
            ||  .|:.:|:::.::.|...||:|:..:::|||||.:|||:|.|..::|..:||.|||.|:...
pombe     1 MG--KSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSA 63

  Fly    66 FCDHVFRTFDMDKNGYIDFKEFLLAIDVTSSGTPEEKLKWAFRMYDVDGNGVIDIQEMTKIVQAI 130
            |.::||..||.|||||||||||:.|:.|||.|...:||.|||::||:|.||:|...||.:||.||
pombe    64 FAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAI 128

  Fly   131 YDMLGA-CSSNRPADSAEERAKNIFAKMDENNDGQLTQDEFLKGCLQDEELSKMLA 185
            |.|:|: .......|:.|:|...||..||:|.|||||.:||.:|..:|..:...|:
pombe   129 YKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALS 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7646	NP_001287124.1	FRQ1	18..178	CDD:227455	78/160 (49%)
ncs1	NP_592879.1	FRQ1	9..179	CDD:227455	79/169 (47%)
		EFh	<36..86	CDD:298682	27/49 (55%)
		EFh	65..125	CDD:238008	33/59 (56%)
		EFh	100..172	CDD:238008	35/71 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
TreeFam	0	0.000	Not matched by this tool.
	5	4.910