Protein Alignment CG7646 and NCS1

DIOPT Version :9

• Sequence 1: NP_001287124.1
• Gene: CG7646 / 40187
• FlyBaseID: FBgn0036926
• Length: 186
• Species: Drosophila melanogaster
• Sequence 2: NP_055101.2
• Gene: NCS1 / 23413
• HGNCID: 3953
• Length: 190
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 83/190 - (43%)
• Similarity: 114/190 - (60%)
• Gaps: 11/190 - (5%)

  Fly     1 MGCLSSKDRLTKEDMEFLKTHTRYDEATIKEWYKGFKQDCPNGRLTPAKFVDMYKMFFPSGNAEE 65
            ||  .|..:|..|.:|.|...|.:.|..:::|||||.:|||:|:|..|.|..:||.|||.|:..:
Human     1 MG--KSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTK 63

  Fly    66 FCDHVFRTFDMDKNGYIDFKEFLLAIDVTSSGTPEEKLKWAFRMYDVDGNGVIDIQEMTKIVQAI 130
            |...||..||.:|:|.|:|.||:.|:.|||.||.:|||:|||::||:|.:|.|...||..||.||
Human    64 FATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAI 128

  Fly   131 YDMLGAC-----SSNRPADSAEERAKNIFAKMDENNDGQLTQDEFLKGCLQDEELSKMLA 185
            |.|:|..     ..|.|    |:|...|||.||:|.||:||..||.:|...|..:.:.|:
Human   129 YQMVGNTVELPEEENTP----EKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALS 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7646	NP_001287124.1	FRQ1	18..178	CDD:227455	75/164 (46%)
NCS1	NP_055101.2	FRQ1	20..179	CDD:227455	75/162 (46%)
		Interaction with IL1RAPL1. /evidence=ECO:0000269|PubMed:12783849	174..190		2/11 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143244
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1369072at2759
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750