DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7646 and ncs-3

DIOPT Version :9

Sequence 1:	NP_001287124.1	Gene:	CG7646 / 40187	FlyBaseID:	FBgn0036926	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_508201.2	Gene:	ncs-3 / 186953	WormBaseID:	WBGene00003565	Length:	199	Species:	Caenorhabditis elegans

Alignment Length:	186	Identity:	78/186 - (41%)
Similarity:	112/186 - (60%)	Gaps:	9/186 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGCLSSK--------DRLTKEDMEFLKTHTRYDEATIKEWYKGFKQDCPNGRLTPAKFVDMYKMF 57
            ||...||        .:||.|:::.|:..|.:.:..:|:|||.|.:|||:|.|...:|..:||.|
Worm     1 MGKSQSKVQTKKKANKKLTTEEVQTLEQVTYFTKKELKKWYKDFVRDCPSGELKMEEFQGIYKQF 65

  Fly    58 FPSGNAEEFCDHVFRTFDMDKNGYIDFKEFLLAIDVTSSGTPEEKLKWAFRMYDVDGNGVIDIQE 122
            ||:|:..:|...||..||.:.:|:|.|.||:.|:.:||.||.:|||.|||.:||||.:|.|...|
Worm    66 FPNGDPSKFAAFVFNVFDDNHDGHISFSEFIAALSITSRGTLDEKLDWAFSLYDVDKDGFITKDE 130

  Fly   123 MTKIVQAIYDMLG-ACSSNRPADSAEERAKNIFAKMDENNDGQLTQDEFLKGCLQD 177
            |..||.|||.|:| .....:..|:.::|.:.||..||.|.|||||::||.:|...|
Worm   131 MADIVDAIYSMIGNMLELPKDEDTPQKRVEKIFTNMDRNLDGQLTREEFKEGSKAD 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7646	NP_001287124.1	FRQ1	18..178	CDD:227455	71/161 (44%)
ncs-3	NP_508201.2	FRQ1	19..187	CDD:227455	73/168 (43%)
		EFh	77..135	CDD:238008	28/57 (49%)
		EFh	110..182	CDD:238008	34/71 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1369072at2759
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820