DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7646 and guca1a

DIOPT Version :9

Sequence 1:	NP_001287124.1	Gene:	CG7646 / 40187	FlyBaseID:	FBgn0036926	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_571945.1	Gene:	guca1a / 140430	ZFINID:	ZDB-GENE-011128-5	Length:	189	Species:	Danio rerio

Alignment Length:	180	Identity:	71/180 - (39%)
Similarity:	105/180 - (58%)	Gaps:	24/180 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TKEDMEFLKTHTRYDEATIKEWYKGFKQDCPNGRLTPAKFVDMYKMFF------PSGNAEEFCDH 69
            |.:|::.::.|.         |||.|..:||:|:||..:|    |.||      |..||  :.:.
Zfish     8 TVDDLQAVEMHL---------WYKKFMTECPSGQLTLHEF----KQFFGLRGLDPKANA--YIEQ 57

  Fly    70 VFRTFDMDKNGYIDFKEFLLAIDVTSSGTPEEKLKWAFRMYDVDGNGVIDIQEMTKIVQAIYDML 134
            :||||||:|:|||||.|::.|:.:...|..|.||:|.|::|||||||.||..|:..|::||..:.
Zfish    58 MFRTFDMNKDGYIDFMEYVAALSLVMRGKMEHKLRWYFKLYDVDGNGCIDRYELLNIIKAIRAIN 122

  Fly   135 GACSSNRPADSAEERAKNIFAKMDENNDGQLTQDEFLKGCLQDEELSKML 184
            |   |.....||||....:|.::|.|.||:|:.|||:.|...|||..:::
Zfish   123 G---SETQESSAEEFTNRVFERIDINGDGELSLDEFVAGARSDEEFMEVM 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7646	NP_001287124.1	FRQ1	18..178	CDD:227455	66/165 (40%)
guca1a	NP_571945.1	EFh	<27..76	CDD:298682	25/54 (46%)
		EFh	54..116	CDD:238008	31/61 (51%)
		EF-hand_7	55..115	CDD:290234	30/59 (51%)
		EFh	90..160	CDD:238008	33/72 (46%)
		EF-hand_7	91..157	CDD:290234	31/68 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576113
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.840