DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nca and USP32

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	XP_011523673.1	Gene:	USP32 / 84669	HGNCID:	19143	Length:	1634	Species:	Homo sapiens

Alignment Length:	159	Identity:	47/159 - (29%)
Similarity:	73/159 - (45%)	Gaps:	18/159 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QNTEFTDAEIQEWYKGFLK-DCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTID 81
            :.::..|.|.:.|   .|| ...:|...:|.|    |...........:|.:|..||.|.|..||
Human   208 EESDIIDLEKRYW---LLKAQSRTGRFDLETF----GPLVSPPIRPSLSEGLFNAFDENRDNHID 265

  Fly    82 FREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTPE 146
            |:|..|.||...||.|.::.|:.|.::|:|.:|.:||.|:.::|.|:.:    |.|....:..||
Human   266 FKEISCGLSACCRGPLAERQKFCFKVFDVDRDGVLSRVELRDMVVALLE----VWKDNRTDDIPE 326

  Fly   147 KRTD------KIFRQMDRNKDGKLSLEEF 169
            ...|      .|....|..|.|.|:||::
Human   327 LHMDLSDIVEGILNAHDTTKMGHLTLEDY 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	47/159 (30%)
USP32	XP_011523673.1	EF-hand_7	252..309	CDD:290234	23/56 (41%)
		EFh	253..309	CDD:238008	23/55 (42%)
		EF-hand_7	286..358	CDD:290234	22/74 (30%)
		UBP12	534..1346	CDD:227847
		DUSP	<535..602	CDD:283896
		Ubiquitin_3	653..740	CDD:291502
		Peptidase_C19	765..>955	CDD:271592
		Peptidase_C19	<1255..1595	CDD:271592
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900