DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nca and KCNIP4

DIOPT Version :9

Sequence 1:NP_788543.1 Gene:Nca / 40186 FlyBaseID:FBgn0013303 Length:190 Species:Drosophila melanogaster
Sequence 2:NP_079497.2 Gene:KCNIP4 / 80333 HGNCID:30083 Length:250 Species:Homo sapiens


Alignment Length:176 Identity:73/176 - (41%)
Similarity:120/176 - (68%) Gaps:0/176 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 KPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFD 73
            :||.||.|:..::||..|:|..|:||..:||||.::.|.||:||..|||.||::.:|..:|..||
Human    69 RPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFD 133

  Fly    74 ANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKM 138
            .:.:|.:.|.:|:..||:..||.:::||.|||::||::.:|||:::|||:|:.|||.|:|.....
Human   134 TDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYP 198

  Fly   139 PEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQ 184
            ...|..|.:..:..|::||:||||.::::||||..:.|.:|:|.:|
Human   199 VLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQ 244

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NcaNP_788543.1 FRQ1 13..179 CDD:227455 68/165 (41%)
KCNIP4NP_079497.2 KIS. /evidence=ECO:0000250 2..44
FRQ1 80..239 CDD:227455 65/158 (41%)
Interaction with KCND2. /evidence=ECO:0000250 237..250 3/8 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0044
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000038
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X31
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.810

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