DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nca and 1700109H08Rik

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_084119.1	Gene:	1700109H08Rik / 77036	MGIID:	1924286	Length:	210	Species:	Mus musculus

Alignment Length:	179	Identity:	47/179 - (26%)
Similarity:	89/179 - (49%)	Gaps:	18/179 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KLKPEVLEDLKQNTEF-TDAEIQEWYKGFLKDCPSGH-----LSVEEFKKIYGNFFPYGDASKFA 65
            |:...:.:.:|...:| .:..|:.:|.  |..||.|.     |....|:.:..|.|...: ....
Mouse     8 KMVESIRKTVKSFKKFEVECLIRLFYS--LVGCPVGKMDNTGLDCNTFRGVLQNIFGMTN-DMLM 69

  Fly    66 EHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYK 130
            ..||..||.:|||.::..|::..|:|..||..|:|:::.|.:|.|:|:.|||::::.:::.:
Mouse    70 NRVFFVFDKDGDGYVNLEEWIKGLAVFLRGTFEEKMRFCFEVYYLNGDAYISQEKIFDMLKS--- 131

  Fly   131 MVGSVMKMPEDESTPEKRTDKI---FRQMDRNKDGKLSLEEFIEGAKSD 176
               |:.:...:|...|...|.:   .::||.:.|||:|..:|.:..|.|
Mouse   132 ---SLFQHSPEEENEEGVKDLVEISLKKMDYDNDGKISFADFEKAVKED 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	46/173 (27%)
1700109H08Rik	NP_084119.1	EFh	71..130	CDD:298682	21/58 (36%)
1700109H08Rik	NP_084119.1	EF-hand_7	105..174	CDD:290234	18/74 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810