DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nca and Kcnip2

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_064479.2	Gene:	Kcnip2 / 56817	RGDID:	70887	Length:	270	Species:	Rattus norvegicus

Alignment Length:	176	Identity:	78/176 - (44%)
Similarity:	120/176 - (68%)	Gaps:	0/176 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFD 73
            :||.||.|::.|:||..|:|..|:||..:||||.::.|.||:||..|||.||:|.:|..:|..||
  Rat    89 RPEGLEQLQEQTKFTRRELQVLYRGFKNECPSGIVNEENFKQIYSQFFPQGDSSNYATFLFNAFD 153

  Fly    74 ANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKM 138
            .|.||::.|.:|:..|||..||.::.:|.|||::|||:.:|.|:::|||:|:.:||.|:|.....
  Rat   154 TNHDGSVSFEDFVAGLSVILRGTIDDRLSWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYP 218

  Fly   139 PEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQ 184
            ...|..|.:..:..|::|||||||.:::|||||..:.|.:|:|.:|
  Rat   219 ALREEAPREHVESFFQKMDRNKDGVVTIEEFIESCQQDENIMRSMQ 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	73/165 (44%)
Kcnip2	NP_064479.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		FRQ1	93..259	CDD:227455	73/165 (44%)
		Interaction with KCND2. /evidence=ECO:0000250\|UniProtKB:Q8R426	257..270		3/8 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810