Protein Alignment Nca and PPP3R2

DIOPT Version :10

• Sequence 1: NP_788543.1
• Gene: Nca / 40186
• FlyBaseID: FBgn0013303
• Length: 190
• Species: Drosophila melanogaster
• Sequence 2: NP_671709.2
• Gene: PPP3R2 / 5535
• HGNCID: 9318
• Length: 170
• Species: Homo sapiens
• Alignment Length: 169
• Identity: 59/169 - (34%)
• Similarity: 91/169 - (53%)
• Gaps: 24/169 - (14%)

  Fly    20 TEFTDAEIQEWYKGFLK---DCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTID 81
            :.|.:.||:...:.|.|   | .||.||||||..:     |....:.....|...||.:|||.:|
Human    13 SHFDNDEIKRLGRRFKKLDLD-KSGSLSVEEFMSL-----PELRHNPLVRRVIDVFDTDGDGEVD 71

  Fly    82 FREFLCALSVTS-RGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTP 145
            |:||:...|..| :|..||||::|||:||:|.:||||..|:.::   :..|||:.:    .:...
Human    72 FKEFILGTSQFSVKGDEEQKLRFAFSIYDMDKDGYISNGELFQV---LKMMVGNNL----TDWQL 129

  Fly   146 EKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQ 184
            ::..||....:|::.|||:|.|||       .::||.|:
Human   130 QQLVDKTIIILDKDGDGKISFEEF-------SAVVRDLE 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	21..175	CDD:444056	56/157 (36%)
PPP3R2	NP_671709.2	FRQ1	20..159	CDD:444056	55/158 (35%)
		Calcineurin A binding. /evidence=ECO:0000250|UniProtKB:P63098	131..136		1/4 (25%)