DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nca and PPP3R1

DIOPT Version :10

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_000936.1	Gene:	PPP3R1 / 5534	HGNCID:	9317	Length:	170	Species:	Homo sapiens

Alignment Length:	31	Identity:	11/31 - (35%)
Similarity:	14/31 - (45%)	Gaps:	7/31 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 GKLLAVVGDSTECLISDSHSGKVISSLRGHK 290
            ||||.::...|..       ||.:||...||
Human    12 GKLLIIIFIVTLW-------GKAVSSANHHK 35

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	21..175	CDD:444056
PPP3R1	NP_000936.1	FRQ1	20..157	CDD:444056	7/23 (30%)
PPP3R1	NP_000936.1	Calcineurin A binding. /evidence=ECO:0000269\|PubMed:12218175, ECO:0000269\|PubMed:12357034, ECO:0000269\|PubMed:17498738, ECO:0000269\|PubMed:22343722, ECO:0000269\|PubMed:23468591, ECO:0000269\|PubMed:26794871, ECO:0000269\|PubMed:27974827, ECO:0000269\|PubMed:8524402	131..136
Blue background indicates that the domain is not in the aligned region.

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