DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nca and guca1d

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_001011661.1	Gene:	guca1d / 494573	ZFINID:	ZDB-GENE-040724-231	Length:	185	Species:	Danio rerio

Alignment Length:	184	Identity:	68/184 - (36%)
Similarity:	105/184 - (57%)	Gaps:	17/184 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFA 65
            ||..::.|...:.||:           ..||..|:::.|||.:::.|.|.|.|......||:.:.
Zfish     1 MGNNHASLDDILAEDM-----------HHWYNKFMRESPSGLITLFELKSILGLQGMNEDANSYV 54

  Fly    66 EHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYK 130
            :.||.|||.:.||.|||.|::.|:|:..:|::.|||||.|.::|.||||.|.:.|:..|.|||..
Zfish    55 DQVFCTFDMDRDGYIDFVEYIAAISLMLKGEINQKLKWYFKLFDQDGNGKIDKDELETIFTAIQD 119

  Fly   131 MVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQ 184
            :..:      .:..||:....||.::|.|.:|:|:|||||||||..|.|:.:|:
Zfish   120 ITRN------RDIVPEEIVALIFEKIDVNGEGELTLEEFIEGAKEHPEIMDMLK 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	63/165 (38%)
guca1d	NP_001011661.1	EF-hand_8	28..76	CDD:290545	20/47 (43%)
		EFh	53..110	CDD:238008	26/56 (46%)
		EF-hand_7	56..114	CDD:290234	27/57 (47%)
		EFh	89..157	CDD:238008	31/73 (42%)
		EF-hand_7	90..154	CDD:290234	27/69 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910