DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nca and hpcal1

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_957458.1	Gene:	hpcal1 / 394139	ZFINID:	ZDB-GENE-040426-1242	Length:	193	Species:	Danio rerio

Alignment Length:	189	Identity:	162/189 - (85%)
Similarity:	173/189 - (91%)	Gaps:	0/189 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFA 65
            ||||||||:||||.||::||||||.|:||||:|||||||||||:||||||||.||||||||||||
Zfish     1 MGKQNSKLRPEVLNDLRENTEFTDHELQEWYRGFLKDCPSGHLTVEEFKKIYANFFPYGDASKFA 65

  Fly    66 EHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYK 130
            ||||||||.|.|.|||||||:.||||||||.|||||:||||||||||||||||.||||||.||||
Zfish    66 EHVFRTFDTNSDATIDFREFIIALSVTSRGGLEQKLRWAFSMYDLDGNGYISRAEMLEIVQAIYK 130

  Fly   131 MVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQS 189
            ||.||||||||||||||||||||||||.:.||:|||||||:|||||||||||||.|..|
Zfish   131 MVSSVMKMPEDESTPEKRTDKIFRQMDTDNDGRLSLEEFIKGAKSDPSIVRLLQSDQSS 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	142/165 (86%)
hpcal1	NP_957458.1	FRQ1	13..179	CDD:227455	142/165 (86%)
		EFh	<36..89	CDD:298682	45/52 (87%)
		EFh	65..126	CDD:238008	52/60 (87%)
		EFh	100..174	CDD:238008	64/73 (88%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4743
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37586
Inparanoid	1	1.050	353	1.000	Inparanoid score	I2220
OMA	1	1.010	-	-		QHG53747
OrthoDB	1	1.010	-	-		D1369072at2759
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100764
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.840