DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nca and guca1c

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_919374.1	Gene:	guca1c / 373099	ZFINID:	ZDB-GENE-030829-1	Length:	188	Species:	Danio rerio

Alignment Length:	183	Identity:	68/183 - (37%)
Similarity:	100/183 - (54%)	Gaps:	17/183 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFA 65
            ||...|.|...:.||:           ..||..|:::.|||.:::.|.|.:........:||.:.
Zfish     1 MGAHASNLDEVLAEDM-----------HYWYNKFMRESPSGLITLFELKNMLEMQGMTEEASSYV 54

  Fly    66 EHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYK 130
            :.||.|||.:|||.|||.|::.|:|:..:|::.|||||.|.::|.||||.|.|.||..|..||..
Zfish    55 DQVFFTFDMDGDGYIDFVEYIAAVSLLLKGEINQKLKWYFKLFDQDGNGKIDRDEMETIFKAIQD 119

  Fly   131 MVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLL 183
            :..|.      |..|:.....|:.::|.|.:|:|:|||||.|||..|.|:.:|
Zfish   120 ITRSY------EIPPDDIVSLIYERIDVNNEGELTLEEFITGAKEHPDIMEML 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	62/165 (38%)
guca1c	NP_919374.1	FRQ1	6..162	CDD:227455	64/172 (37%)
		EFh	53..110	CDD:238008	28/56 (50%)
		EFh	89..157	CDD:238008	31/73 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910