DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nca and HPCA

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_002134.2	Gene:	HPCA / 3208	HGNCID:	5144	Length:	193	Species:	Homo sapiens

Alignment Length:	189	Identity:	161/189 - (85%)
Similarity:	176/189 - (93%)	Gaps:	0/189 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFA 65
            ||||||||:||:|:||::||||::.|:||||||||||||:|.|:|:||||||.||||||||||||
Human     1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFA 65

  Fly    66 EHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYK 130
            ||||||||.|.|||||||||:.||||||||:|||||.||||||||||||||||:||||||.||||
Human    66 EHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYK 130

  Fly   131 MVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQS 189
            ||.||||||||||||||||:|||||||.|.||||||||||.||||||||||||||||.|
Human   131 MVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQCDPSS 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	140/165 (85%)
HPCA	NP_002134.2	FRQ1	13..179	CDD:227455	140/165 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	139	1.000	Domainoid score	I4789
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	353	1.000	Inparanoid score	I2255
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53747
OrthoDB	1	1.010	-	-		D1369072at2759
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	1	1.000	-	-		otm41635
orthoMCL	1	0.900	-	-		OOG6_100764
Panther	1	1.100	-	-	LDO	PTHR23055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4678
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870