Protein Alignment Nca and NCS1

DIOPT Version :9

• Sequence 1: NP_788543.1
• Gene: Nca / 40186
• FlyBaseID: FBgn0013303
• Length: 190
• Species: Drosophila melanogaster
• Sequence 2: NP_055101.2
• Gene: NCS1 / 23413
• HGNCID: 3953
• Length: 190
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 116/183 - (63%)
• Similarity: 149/183 - (81%)
• Gaps: 0/183 - (0%)

  Fly     1 MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFA 65
            |||.||||||||:|:|.:.|.||:.|:|:|||||:||||||.|....|:|||..|||:||.:|||
Human     1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFA 65

  Fly    66 EHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYK 130
            ..||..||.|.||.|:|.||:.||||||||.|::||:|||.:||||.:|||:|.|||:||.|||:
Human    66 TFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQ 130

  Fly   131 MVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLL 183
            |||:.:::||:|:|||||.|:||..||:|.||||:|:||.||:|:|||||:.|
Human   131 MVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQAL 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	101/165 (61%)
NCS1	NP_055101.2	FRQ1	20..179	CDD:227455	99/158 (63%)
		Interaction with IL1RAPL1. /evidence=ECO:0000269|PubMed:12783849	174..190		7/10 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53747
OrthoDB	1	1.010	-	-		D1369072at2759
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100764
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730