DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nca and Rcvrn

DIOPT Version :9

Sequence 1:	NP_788543.1	Gene:	Nca / 40186	FlyBaseID:	FBgn0013303	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_033064.1	Gene:	Rcvrn / 19674	MGIID:	97883	Length:	202	Species:	Mus musculus

Alignment Length:	193	Identity:	102/193 - (52%)
Similarity:	143/193 - (74%)	Gaps:	7/193 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKQNSK---LKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDAS 62
            ||  |||   |..|:||:|:.||:||:.|:..||:.|||:||||.::.:||:.||..|||..|..
Mouse     1 MG--NSKSGALSKEILEELQLNTKFTEEELSAWYQSFLKECPSGRITRQEFESIYSKFFPDSDPK 63

  Fly    63 KFAEHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTA 127
            .:|:||||:||||.|||:||:|::.||.:|:.||..|||:||||:||:||||.||:.|:||||.|
Mouse    64 AYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIVMA 128

  Fly   128 IYKMV--GSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQ 188
            |:||:  ..|..:|:||:|||||.:||:....:.:|.||:.||||||..::..|:||:|.:||
Mouse   129 IFKMIKPEDVKLLPDDENTPEKRAEKIWAFFGKKEDDKLTEEEFIEGTLANKEILRLIQFEPQ 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nca	NP_788543.1	FRQ1	13..179	CDD:227455	89/167 (53%)
Rcvrn	NP_033064.1	FRQ1	14..182	CDD:227455	89/167 (53%)
		EFh	<37..90	CDD:298682	28/52 (54%)
		EFh	65..127	CDD:238008	39/61 (64%)
		EFh	101..175	CDD:238008	41/73 (56%)
		Interaction with GRK1. /evidence=ECO:0000250\|UniProtKB:P21457	189..192		2/3 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53747
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920