| Sequence 1: | NP_001246838.1 | Gene: | Ac76E / 40180 | FlyBaseID: | FBgn0004852 | Length: | 1312 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_598582.3 | Gene: | Phlpp1 / 98432 | MGIID: | 2138327 | Length: | 1687 | Species: | Mus musculus |
| Alignment Length: | 947 | Identity: | 189/947 - (19%) |
|---|---|---|---|
| Similarity: | 295/947 - (31%) | Gaps: | 322/947 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 373 GLPISRPQHATNCVN--------------MGLQMIDA--IRHVREATGINVDMRIGIHTGN---- 417
Fly 418 -VLCGVLGLRKWQFDVWSDDVTLA---------NHMESGGV----------AGRVHITKQTLDFL 462
Fly 463 GDKFEVEQGEGGNRDAYLADHKVESYLIVPPKP------------------------AYTYSVPR 503
Fly 504 VVECIEQNDPSPTTEETKEIKETDQSHEATDVADVLLPVTVAPPPAIVDE--KMSPT--SINSQE 564
Fly 565 APLHAPLASAASMSIKELSEEEDEADEAT--AVTEPLMHRDQDGKNDK--EPKANGGHRGSGDSA 625
Fly 626 ASESVAKSAALSLPADDL-LSMSGSESGISNSGAQAQSSNPASVTPTAAAPAGGAASNSLTVAEA 689
Fly 690 PERSRRKLSVQGLMSFAD--RRRSSG---------AFIEGRKLSIHSGESFRSHAGHVTRNRPSS 743
Fly 744 KMTKYVECWGADRPFANIAESKLVKNIGLASIAMIES----------NLLP----------PERK 788
Fly 789 CFNFNFFGPPTE--------LKPFTMWYRNTPREAMYRAQPDTHFRFDLICAFV------LFLSL 839
Fly 840 AVVQLIVIELNLALLGSLLASFVSLALFLYLSNMSVPDVHASTTERNGPGQVVASSRYLRLAMFV 904
Fly 905 VVNILISSCAVFSVINYTVPDGVSKEPSSNQTILESNFSSVFVNSTLEDVQLWEIDYAIPIAPVF 969
Fly 970 LYCCAISLAAISAFLRSGFILKLIAMLVAVIAQVTVLGYSDLFEMYNDANITHGLPLEIKGFLLL 1034
Fly 1035 --------LVIILVLHTLDRQGEYVARTDFLWKAKLKVEQEEVETMRGINKI-LLENILPAHVAT 1090
Fly 1091 HF-----LHLERS------------TELYHESYSCVAVMFASIPNYKEFYDETDVNKQGLECLRL 1138
Fly 1139 LNEIICDFDKLLLKPKFSGIEKIKTIASTYMCASGLR 1175 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ac76E | NP_001246838.1 | AC_N | <67..289 | CDD:292831 | |
| CYCc | 259..467 | CDD:214485 | 29/133 (22%) | ||
| Guanylate_cyc | 311..469 | CDD:278633 | 29/135 (21%) | ||
| BASP1 | 510..667 | CDD:283191 | 39/165 (24%) | ||
| CYCc | 1079..1283 | CDD:214485 | 29/114 (25%) | ||
| Guanylate_cyc | 1101..1305 | CDD:278633 | 20/75 (27%) | ||
| Phlpp1 | NP_598582.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..96 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 230..406 | 49/224 (22%) | |||
| PH_PHLPP-like | 491..587 | CDD:270131 | 17/111 (15%) | ||
| PH | 511..592 | CDD:278594 | 12/93 (13%) | ||
| LRR_RI | 581..885 | CDD:238064 | 76/387 (20%) | ||
| LRR_8 | 594..659 | CDD:290566 | 17/100 (17%) | ||
| LRR 1 | 594..615 | 6/25 (24%) | |||
| leucine-rich repeat | 597..617 | CDD:275380 | 6/19 (32%) | ||
| LRR 2 | 617..638 | 5/45 (11%) | |||
| leucine-rich repeat | 618..648 | CDD:275380 | 8/57 (14%) | ||
| LRR_8 | 647..726 | CDD:290566 | 22/114 (19%) | ||
| LRR 3 | 648..669 | 5/30 (17%) | |||
| LRR 4 | 671..692 | 8/40 (20%) | |||
| leucine-rich repeat | 672..694 | CDD:275380 | 7/41 (17%) | ||
| LRR 5 | 694..715 | 4/20 (20%) | |||
| leucine-rich repeat | 695..717 | CDD:275380 | 4/21 (19%) | ||
| LRR 6 | 717..739 | 7/29 (24%) | |||
| leucine-rich repeat | 718..740 | CDD:275380 | 6/29 (21%) | ||
| LRR 7 | 740..760 | 4/20 (20%) | |||
| leucine-rich repeat | 741..764 | CDD:275380 | 5/23 (22%) | ||
| LRR 8 | 764..785 | 4/20 (20%) | |||
| LRR_RI | 768..1030 | CDD:238064 | 33/140 (24%) | ||
| leucine-rich repeat | 768..788 | CDD:275380 | 4/19 (21%) | ||
| LRR 9 | 788..809 | 5/20 (25%) | |||
| leucine-rich repeat | 789..809 | CDD:275380 | 5/19 (26%) | ||
| leucine-rich repeat | 810..851 | CDD:275380 | 8/40 (20%) | ||
| LRR 10 | 829..850 | 3/20 (15%) | |||
| LRR 11 | 851..872 | 7/26 (27%) | |||
| leucine-rich repeat | 852..874 | CDD:275380 | 6/27 (22%) | ||
| LRR 12 | 874..895 | 4/22 (18%) | |||
| leucine-rich repeat | 875..897 | CDD:275380 | 4/23 (17%) | ||
| LRR_8 | 896..954 | CDD:290566 | 3/4 (75%) | ||
| LRR 13 | 897..918 | 2/3 (67%) | |||
| leucine-rich repeat | 898..919 | CDD:275380 | 2/2 (100%) | ||
| LRR 14 | 919..940 | ||||
| leucine-rich repeat | 920..943 | CDD:275380 | |||
| LRR 15 | 943..964 | ||||
| leucine-rich repeat | 944..967 | CDD:275380 | |||
| LRR 16 | 969..989 | ||||
| LRR_8 | 970..1028 | CDD:290566 | |||
| leucine-rich repeat | 970..993 | CDD:275380 | |||
| LRR 17 | 993..1014 | ||||
| leucine-rich repeat | 994..1017 | CDD:275380 | |||
| LRR 18 | 1017..1038 | ||||
| LRR 19 | 1040..1061 | ||||
| LRR 20 | 1062..1083 | ||||
| leucine-rich repeat | 1063..1085 | CDD:275380 | |||
| LRR 21 | 1085..1106 | ||||
| PP2Cc | 1124..1376 | CDD:214625 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1414..1465 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1604..1687 | ||||
| PDZ-binding | 1685..1687 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2114 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||