DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ac76E and CG14877

DIOPT Version :9

Sequence 1:	NP_001246838.1	Gene:	Ac76E / 40180	FlyBaseID:	FBgn0004852	Length:	1312	Species:	Drosophila melanogaster
Sequence 2:	NP_650507.1	Gene:	CG14877 / 41929	FlyBaseID:	FBgn0038380	Length:	254	Species:	Drosophila melanogaster

Alignment Length:	224	Identity:	34/224 - (15%)
Similarity:	81/224 - (36%)	Gaps:	76/224 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1062 LKVEQEEVETMRGINKILLENILPAHVATHFLHLERSTELYHESYSCVAVMFASIPNYKEFYDET 1126
            |||.::::.:         ::::|:|:...:|..:...:   .|...:..|...|.
  Fly    65 LKVAEQQIRS---------KSLIPSHIDFEWLAHDTKCD---ASLGVIKAMDGIIK--------- 108

  Fly  1127 DVNKQGLECLRLLNEIICDFDKLLLKPKFSGIEKIKTIASTYMCASGLRPGKEDGATSRSFADEK 1191
                   :|.:::...:||:       ..:.:.:|    :.|..:.| .|....|.::..| ::|
  Fly   109 -------QCAQVIFGPVCDY-------SLAAVSRI----TKYFNSQG-TPLISVGGSTYDF-EQK 153

  Fly  1192 RTEEHNVVILVEFAIALMSILDSINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVA 1256
            :|:.::     ||.:.|.:  ..::.|:.....:.:...|.                ||:::...
  Fly   154 KTDCND-----EFYMLLRT--GMLSFETISELTINVMKRHN----------------WSHSIFYY 195

  Fly  1257 SR--------MDSCGVM----GRLQTTEN 1273
            .|        |.:|.:|    |:....||
  Fly   196 ERDGQRSVAGMHTCFLMMKSLGKQMRNEN 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831
		CYCc	259..467	CDD:214485
		Guanylate_cyc	311..469	CDD:278633
		BASP1	510..667	CDD:283191
		CYCc	1079..1283	CDD:214485	31/207 (15%)
		Guanylate_cyc	1101..1305	CDD:278633	28/185 (15%)
CG14877	NP_650507.1	Periplasmic_Binding_Protein_Type_1	46..>241	CDD:299141	34/224 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900