Protein Alignment Ac76E and CG42637

DIOPT Version :10

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Alignment Length: 829
• Identity: 177/829 - (21%)
• Similarity: 289/829 - (34%)
• Gaps: 248/829 - (29%)

  Fly    20 NLIVKADGNATQPKAMTSSAARMNDALSASLADLSEQENGTTAEDIHLNDLYTRYRQRLRKSLFR 84
            |..:.|....|:...:|...|:      .||.|:.|.      |||.|:||:
  Fly   611 NSFIGASVEPTRILLVTDYCAK------GSLYDIIEN------EDIKLDDLF------------- 650

  Fly    85 SGLLTSLLACVVSIIIGIVYGQHLVQTMLLVLAALISGS--ILTA---LQFPAVLSSPAAALAFA 144
                      :.|:|..::.|...:....||....:..|  ::|:   ||
  Fly   651 ----------IASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQ--------------- 690

  Fly   145 IVTTFSLGTIAAITGDE-------------LAPL------------PMYALFLCIHSMLPISWP- 183
             ||.|.|..:.....:|             .||.            .:||..:.::.:.....|
  Fly   691 -VTDFGLHELRQCAENESIGEHQHYRNQLWRAPELLRNHIHGSQKGDVYAFAIIMYEIFSRKGPF 754

  Fly   184 ----------VSVVLAL-------FMTAIHIVYRIGTSPDYA---------------PNLPMLFG 216
                      |..|..|       |...:..:....:.|||.               |...::..
  Fly   755 GQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRN 819

  Fly   217 EIVMLASASVSGLYYRIMSDAAHNRTVDGTRTGIEQRVKLECEREQQ-EQLLLSVIPAYIAAEVK 280
            .:..:.......:..::|.  ...:..:.....:.:|.:|.||.:.: |.||..::|..:|.::.
  Fly   820 RLKKMRGGKTKNIMDQMME--MMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLT 882

  Fly   281 RSIMLKMADACQRAGGQASTSATRFHELHVQRHTNVTILFADIVNFTPLSSSLTASDLVKTLNDL 345
            .              ||.....:  ::|       |||.|:|||.||.:|:..|...:|..||||
  Fly   883 M--------------GQGVEPVS--YDL-------VTIYFSDIVGFTAMSAESTPLQVVNFLNDL 924

  Fly   346 FGRFDQIAQENQCLRIKILGDCYYCVSGLPISR-PQHATNCVNMGLQMIDAIRHVREATGIN--V 407
            :..||:|.:.....:::.:||.|..||||||.. .:||....:|.|:::.|::..|.|...|  :
  Fly   925 YTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETL 989

  Fly   408 DMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGRVHIT---KQTLDFLGDKFEVE 469
            .:|||:|||.|:.||:||...::.::.|.|..|:.|||.|.|.::||:   |..||.||..:..|
  Fly   990 KLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITE 1054

  Fly   470 ---------QGE-------GGNRDAYLADHKVESYLIVPPKPAYTYSVPRVVECIEQNDPSPTTE 518
                     :|:       |.|.:|  ...|:...:.:||.   .:|.||         .||
  Fly  1055 KRGLVNMKGKGDVVTWWLTGANENA--IQKKLVDMMDMPPP---LFSRPR---------KSP--- 1102

  Fly   519 ETKEIKETDQSHEATDVADVLLPVTVAPPPAIVDEKMSPTSINSQEAPLH-APLASAASMSIKEL 582
                                               |::|.|.......:| ....|....::...
  Fly  1103 -----------------------------------KLNPDSRQPSIQAMHFCGTGSRRQSTVPRA 1132

  Fly   583 SEEEDEADEATAVTE-PLM--HRDQDGKNDKEPKANG---GHRGSGDSAASESVAKSAALSLPA- 640
            .:.|.......:|.| |.|  .||:|   .:.|..||   ||...|      ::.:||..||..
  Fly  1133 MDGESTYSLQGSVRESPRMVSKRDRD---RERPPINGLGAGHFVGG------ALLESAQASLSTL 1188

  Fly   641 ------DDLLSMSGSESGISNSGA------QAQSSNPASVTP---TAAAPAGGAASNSLTVAEAP 690
                  :....|.|...|:|.||:      .|.....|.|.|   .:||.......|....|:..
  Fly  1189 NHSETNETNCDMDGGSGGVSGSGSGLVRQPNALHKPLAMVRPHRIISAAQLPQLGDNDDDSADTL 1253

  Fly   691 ERSRRKLSVQGLMSFADRRRSSGAFIEGRKLSIHSGESFRSHAGHVTRN 739
            .|..|.|....:...  |:|.....:...|||.::..|..:....::.|
  Fly  1254 LRESRSLDPMPMQQL--RKRHDRVKLPPSKLSKNNSRSLDTGVSLISGN 1300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AcyC	72..470	CDD:441717	103/476 (22%)
		Guanylate_cyc	310..469	CDD:425528	62/164 (38%)
		Guanylate_cyc	1101..1305	CDD:425528
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593
		PK_GC-A_B	543..827	CDD:270944	42/266 (16%)
		HNOBA	<833..881	CDD:462234	10/49 (20%)
		CYCc	860..1052	CDD:214485	71/214 (33%)