Protein Alignment Ac76E and CG32301

DIOPT Version :9

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_728724.2
• Gene: CG32301 / 38285
• FlyBaseID: FBgn0052301
• Length: 1111
• Species: Drosophila melanogaster
• Alignment Length: 1341
• Identity: 318/1341 - (23%)
• Similarity: 503/1341 - (37%)
• Gaps: 441/1341 - (32%)

  Fly   103 VYGQHLVQTMLLVLAALISGSILTALQFPAVLSSPAAALAFAIVTTFSLGTIAAITGDELAPLPM 167
            ||.:|    ..||..||::..|:..    .:|......|.|::|...          |.|..||.
  Fly    38 VYHRH----CHLVSVALVTQLIIVI----EILMLIHVILLFSVVKNI----------DFLTVLPY 84

  Fly   168 YALFLCIHSML-PISWP-----------VSVVLALFMTAIHIVYRI------GTSPDYAP----- 209
            :|:.|...|:| |...|           ||.::||.:||:.::..|      ...|.|..
  Fly    85 FAVMLLTPSILMPSREPNVEQYESIAILVSCLMALLLTAMDLILPICYFRPFSLVPSYDHVVIVL 149

  Fly   210 ---NLPMLF---GEIVMLASASVSGLYYRIMS--------DAAHNRTVDGT-------------- 246
               ..|:.|   |....|..| ||..|:..|:        |.....|..|.
  Fly   150 IYLMFPIAFVKNGRAYFLGLA-VSLFYFGYMALIDKISTLDKVWELTAYGAYLFFLNMLCMFLSR 213

  Fly   247 ------RTGIEQRVKL-------ECEREQQEQLLLSVIPAYIAAEVKRSIMLKMADACQRAGGQA 298
                  |:||..|.::       :...::::.||.|:||..:|..::.:|...:.:.....
  Fly   214 FQEYNMRSGILSRYQVVYQNLVFQMAMKEEKALLDSIIPVTLARSLQDAIASHIEEDPSNL---- 274

  Fly   299 STSATRFHELHVQRHTNVTILFADIVNFTPLSSSLTASDLVKTLNDLFGRFDQIAQENQCLRIKI 363
             ...|:...|.::.|..|:||.||:|:||.|::::..||||..|::||..||..|..|:..|||.
  Fly   275 -MPFTKTRHLFMEPHPEVSILEADMVDFTGLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKF 338

  Fly   364 LGDCYYCVSGLPISRPQHATNCVNMGLQMIDAIRHVREATGINVDMRIGIHTGNVLCGVLGLRKW 428
            |||.|.||:|:|...|.||..|||..|.||:..|.|.:.....:|:|||:|:|.:|.|::||.||
  Fly   339 LGDSYTCVTGIPSYFPTHANACVNQALDMIEISREVSKRRNKKIDLRIGVHSGEILAGIIGLTKW 403

  Fly   429 QFDVWSDDVTLANHMESGGVAGRVHITKQTLDFLGDKFEVEQG-EGGNRDAYLADHKVESYLIVP 492
            |||:||.||.:.|.:||.|:.|.|||:.:||..|.:.:..|:| :....|..|....:.:|||
  Fly   404 QFDIWSKDVDITNRLESSGLPGMVHISSRTLGLLDNHYVYEEGTDTAKLDPLLQRSNLSTYLI-- 466

  Fly   493 PKPAYTYSVPRVVECIEQNDPSPTTEETKEIKETD-------------QSHEATDV---ADVLLP 541
                              ....|..|:|.::::.:             |.:|...|   .|::|.
  Fly   467 ------------------RSRLPNFEDTDDLEDDNFSLNDYRFSFSFSQDYEDIQVKAQRDMILE 513

  Fly   542 VTVAPPPAIVDEKMSPTSINSQEAPLHAPLASAASMSIKELSEEEDEADEATAVTEPLMHRDQDG 606
            |.                        |.|:....:..|:                .| |||
  Fly   514 VE------------------------HMPVNRVQTCKIR----------------RP-MHR---- 533

  Fly   607 KNDKEPKANGGHRGSGDSAASESVAKSAALSLPADDLLSMSGSESGISNSGAQAQSSNPASVTPT 671
                              .|.|.:.:.....|.:..|.:
  Fly   534 ------------------IAKEDINEEYRFHLESYYLFT-------------------------- 554

  Fly   672 AAAPAGGAASNSLTVAEAPERSRRKLSVQGLMSFADRRRSSGAFIEGRKLSIHSGESFRSHAGHV 736
                                                                    :|||
  Fly   555 --------------------------------------------------------TFRS----- 558

  Fly   737 TRNRPSSKMTKYVECWGADRPFANIAESKLVKNIGL---ASIAMIESNLLPPERKCFNFNFFGPP 798
                           |..:..|..:.:..:..::|:   |...:|..:||
  Fly   559 ---------------WRMEWSFNKMRDLLMKYSLGMMVFAGATIIAMDLL--------------- 593

  Fly   799 TELKPFTMWYRNTPREAMYRAQPDTHFRFDLICAFVLFLSLAVVQLIVIELNLALLGSLLASFVS 863
                        ...|||           |....|.|||.:.:..|:.....|.|.|..|:....
  Fly   594 ------------VKSEAM-----------DYTMLFSLFLLILLPLLLASYKKLWLRGRRLSPITQ 635

  Fly   864 LALFLYLSNMSVPDVHASTTERNGPGQVVASSRYLRLAMFVVVNILISSCAVFSVINYTVPDGVS 928
            ...||....:...|             ::..|.::|:.:.::|..|:          |.:
  Fly   636 PTFFLSRWFIKASD-------------LIEKSVFVRIPLAIMVLFLL----------YVM----- 672

  Fly   929 KEPSSNQTILESNFSSV---FVNSTLEDVQ-------LWEIDYAIPIAPVFLYCCAISLAAISAF 983
                |::|:...:.:.:   .:||.|.:::       .|.:.||:    |.:....:.:..|...
  Fly   673 ----SSETVFSCDIARLELEIINSELHNLRPQMLCFMPWGVTYAV----VIVLSLMLVIIGIPLI 729

  Fly   984 LRSGFILKLIAMLVAVIAQVTVLGYSDL-FEMYNDANITHGLPLEIKGFLLLLVIILVLHTLDRQ 1047
            ::.|..|.::...|     :||..|... ||.....||.....|....:::...|::|:    |:
  Fly   730 IKLGVGLAILGSHV-----ITVHAYYGFAFERSQTTNIGVTSSLAHSWYMVAFFIVVVV----RE 785

  Fly  1048 G--EYVARTDFLWKAKLKVEQEEVETMRGINKILLENILPAHVATHFLHLERSTELYHESYSCVA 1110
            |  .|:.:..:......:.:.|..:......||::.||||.|||..|....||.:||:|::|.||
  Fly   786 GYLNYILKASYFMSMCFEKKHELTKVKTRTIKIIMANILPTHVAEVFKVRRRSDQLYYENFSQVA 850

  Fly  1111 VMFASIPNYKEFYDETDVNKQGLECLRLLNEIICDFDKLLLK-PKFSGIEKIKTIASTYMCASGL 1174
            ||||:|.||       :.:|.|   ||.|:|:||.||:||:. ..:..|||||.:..||:.|.||
  Fly   851 VMFATIENY-------EADKSG---LRALHEMICYFDELLVNYQSWYKIEKIKVMGWTYLAACGL 905

  Fly  1175 R--------------PGKEDGATSRS----FA----DE------------KRTEEHNVVILVEFA 1205
            .              ..:|.....:|    ||    ||            ...:::.::::.|||
  Fly   906 HVDHYTDFSVSVPISTNRESDKLQKSGSVRFAPMDGDEIMIKDLHPTQATTNEDDNTILVMTEFA 970

  Fly  1206 IALMSILDSI-------NRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCG 1263
            :.|:.||..|       .::|.....|:||:.||||:|||:|..||.||||.:|||:||||.|.|
  Fly   971 LNLLRILRDIRSKGIFFEKDSKLTGSLKIGIAHGPVMAGVVGLSKPHYDIWGHTVNMASRMTSTG 1035

  Fly  1264 VMGRLQTTENTAKILMTAGYECECRGLTYVKGKGNLVTYFV 1304
            |...:..||:||.:|......|..||:|:|||.|.:.||.|
  Fly  1036 VRDGIHVTESTANVLRDFNIRCTYRGMTFVKGVGQVPTYLV 1076

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831	54/249 (22%)
		CYCc	259..467	CDD:214485	82/207 (40%)
		Guanylate_cyc	311..469	CDD:278633	73/157 (46%)
		BASP1	510..667	CDD:283191	20/172 (12%)
		CYCc	1079..1283	CDD:214485	91/245 (37%)
		Guanylate_cyc	1101..1305	CDD:278633	92/246 (37%)
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	74/155 (48%)
		CYCc	812..1051	CDD:214485	92/248 (37%)
		Nucleotidyl_cyc_III	841..1076	CDD:299850	91/244 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453937
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181177at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940