Protein Alignment Ac76E and ACXC

DIOPT Version :9

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Alignment Length: 1341
• Identity: 318/1341 - (23%)
• Similarity: 529/1341 - (39%)
• Gaps: 395/1341 - (29%)

  Fly    63 EDIHLNDLYTRYRQRLRKSLFRSGLLTSLLACVVSIIIGIVYGQHL----------VQTMLLVLA 117
            ::::|.:.|..|:.||..|......:..::..:..:.|.::|.||.          |.:.:|||.
  Fly    41 KELNLEEEYRYYQVRLMVSNLTIFYVLFIILAMSFLTIELLYVQHYNAVFFNFVIRVVSTILVLT 105

  Fly   118 ALISGSILTALQFPA-----VLSSPAAALAFAIVTTFSLGTIAAITGDELAPLPMYALF----LC 173
            .|   ||....:|.:     :::|...::...::|...:.:......|    .|:...|    ||
  Fly   106 VL---SINFCEKFVSRHRWVMIASSVLSVYLVVLTDIVMISYHFYKND----WPLNTSFDVFTLC 163

  Fly   174 -IHSMLPI---------SWPVSVV-LALFMTAI--HIVYRIGTSPDYAPNLPMLFGEIVMLASAS 225
             |:..|||         :..||:: :|.||.::  :.||....|..|    .::..:|:.....:
  Fly   164 MIYMFLPIPSIKGAALLASSVSLIYVAFFMHSLTFNAVYTDRDSFGY----DVISTDILHNLGFN 224

  Fly   226 VSGLYYRIMSDAAHNRTVDGTRTGIEQRVKLECEREQQEQLLLSVIPAYIAAEVKRSIMLKMADA 290
            :.|:::|||:|.....:.......|.:...|.....|:..||.|::|..||..|:..|..|:.
  Fly   225 MMGIFFRIMNDTMVRASFLDRHQFIMEETWLRHALLQESILLDSILPPQIAKPVQEKIKSKIT-- 287

  Fly   291 CQRAGGQASTSATRFHE--------LHVQRHTNVTILFADIVNFTPLSSSLTASDLVKTLNDLFG 347
                  |:..|..||..        :.:|.|.:|:||:||:||:|.|:::||..:|||.|:||:|
  Fly   288 ------QSENSPDRFQMGPRTTESFMAIQIHPDVSILYADVVNYTHLTTTLTVGNLVKVLHDLYG 346

  Fly   348 RFDQIAQENQCLRIKILGDCYYCVSGLPISRPQHATNCVNMGLQMIDAIRHVREATGINVDMRIG 412
            |||..|...:..|||.||||||||:||....|.||..||::|:.||..|:.||...|:::|||||
  Fly   347 RFDIAASNFKVQRIKFLGDCYYCVAGLTTPDPDHAKCCVSLGISMISNIQEVRAERGLDIDMRIG 411

  Fly   413 IHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGRVHITKQTLDFLGDKFEVEQGEGGNRD 477
            :|:|::|.|::|..|.|||:|..||.:|||:||.|..|.||::.:||..|.
  Fly   412 VHSGSLLAGIIGEAKLQFDIWGTDVEIANHLESTGEPGYVHVSGRTLSMLN-------------- 462

  Fly   478 AYLADHKVESYLIVPPKPAYTYSVPRVVECIEQNDPSPTTEETKEIKETDQSHEATDVADVLLPV 542
                                                                             
  Fly   463 ----------------------------------------------------------------- 462

  Fly   543 TVAPPPAIVDEKMSPTSINSQEAPLHAPLASAASMSIKELSEEEDEADEATAVTEPLMHRDQDGK 607
                                                                             
  Fly   463 ----------------------------------------------------------------- 462

  Fly   608 NDKEPKANGGHRGSGDSAASESVAKSAALSLPADDLLSMSGSESGISN-----------SGAQAQ 661
                                           |||..: :||::...|:           :|..|:
  Fly   463 -------------------------------PADYTI-LSGTQKAQSDPVLQYIHTYLLTGQVAR 495

  Fly   662 SSNPASVTPTAAAPAGGAASNSLTVAEAPERSRRKLSVQGLMSFADRRRSSGAFIEGRKLSIHSG 726
            .|...|:        ||..|:|:...::.:|.|.....|.  |..|..|
  Fly   496 ESFITSI--------GGVRSSSVLEVKSIDRIRSSRPSQS--SMTDEFR---------------- 534

  Fly   727 ESFRS-HAGHVTRNRPSSKMTKYVECWGADRPFANIAESKLVKNIGLASIAMIESNLLPPERKCF 790
            |.||: ..|.:..|.|..:.|:.            ....|..:.||:...|..:|:|
  Fly   535 EEFRNMPVGGINLNSPCCRRTRL------------DTHKKTQREIGIFCAAFKDSSL-------- 579

  Fly   791 NFNFFGPPTELKPFTMWYRNTPREAMYRAQPDTHFRFDLICAFVLFLSLAVVQLIVIELNLALLG 855
                                   |..|..|||..|:..::.|:.:...|..:|  ::..|.:...
  Fly   580 -----------------------EWNYLHQPDFIFKSSMLLAWGIGCCLIYIQ--IVTNNFSCTA 619

  Fly   856 SLLASFVSLALFLYLSNMSVPDVHASTT-ERNGPGQVVASSRY--------------LRLAMFVV 905
            .::   |.|..|.:|:::.....:.:.. .::|..:.....:|              :.|.:.|.
  Fly   620 CIV---VDLVTFFFLTSLLCLAWYKNVCWWKSGRYEFRIYGKYSCMAFHIFEKIQHSVSLRITVY 681

  Fly   906 VNILISSCAVFSVINYTVPDGVSKEPSSNQTILESNFSSVFVNSTLEDVQLWEIDYAIPIAP-VF 969
            :.||.|..||.|:|..          :.::.:.|.::..       ..:..:|:|......| ||
  Fly   682 LGILFSYYAVISLIML----------NCDRDMYELSYIE-------SKIYHYEMDRDTCFHPWVF 729

  Fly   970 LYCCAISLAAISAFLRSGFILKLIAMLVAVIAQVTVLGYSDLFEMYNDANITHGLPLEIKGFLLL 1034
            ....::.|.....|.|..|.||::......:|.:.::.:...|...:.|..|..:..|:...|.:
  Fly   730 TNMISLILGISYTFARIPFGLKIVISCCETLAYLLIVFFQFAFIFQHSATTTPFMKAELAHCLRV 794

  Fly  1035 LVIILVLHTLDRQGEYVARTDFLWKAKLKVEQEEVETMRGINKILLENILPAHVATHFLHLERST 1099
            .:::|.::..:||.|:..:.::.....|:.:|:..:.......|||.||||:||...:|:.....
  Fly   795 CMMLLTMYAKERQSEFNTKMNYKLNVDLQNKQKAADLTNQSIIILLNNILPSHVVDLYLNSLAKH 859

  Fly  1100 ELYHESYSCVAVMFASIPNYKEFYDETDVNKQGLECLRLLNEIICDFDKLLLK-PKFSGIEKIKT 1163
            |||:|:|..|:||||.:.|:          ...|..||:||:||..||:||.. .::..:||||.
  Fly   860 ELYYENYRMVSVMFAMLINF----------PMNLPSLRVLNDIITQFDRLLTAYREYYVVEKIKV 914

  Fly  1164 IASTYMCASGLRPG------------------KEDGATSRSFADEKRTEEHN----VVILVEFAI 1206
            :..|||.|.||...                  :.:.|.:....||....:.|    |.|:..||:
  Fly   915 VGCTYMAACGLDFNLASNIRQTDHFRNSSLHVEVEHARNHRMTDENYDSDMNNDEVVFIMTTFAL 979

  Fly  1207 ALMSILDSINR--------ESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCG 1263
            .||..|.:.||        .|..:.::.||::.|.::|||:||.:|.||||.|.||:||||:|.|
  Fly   980 DLMRTLAACNRAYSSSFFERSLSQGKICIGISSGEIMAGVVGASQPHYDIWGNPVNMASRMESTG 1044

  Fly  1264 VMGRLQTTENTAKILMTAGYECECRGLTYVKGKGNLVTYFV 1304
            :.|.:|.||.:||||.....:|..||:|:|||:|::.||||
  Fly  1045 LPGHIQVTEESAKILQEFDIKCIYRGMTFVKGRGDIPTYFV 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831	56/253 (22%)
		CYCc	259..467	CDD:214485	92/215 (43%)
		Guanylate_cyc	311..469	CDD:278633	78/157 (50%)
		BASP1	510..667	CDD:283191	9/167 (5%)
		CYCc	1079..1283	CDD:214485	85/234 (36%)
		Guanylate_cyc	1101..1305	CDD:278633	87/235 (37%)
ACXC	NP_609593.1	AC_N	<33..285	CDD:292831	55/254 (22%)
		CYCc	293..468	CDD:214485	83/349 (24%)
		Nucleotidyl_cyc_III	307..466	CDD:299850	80/333 (24%)
		CYCc	833..1060	CDD:214485	85/236 (36%)
		Nucleotidyl_cyc_III	861..1085	CDD:299850	85/233 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454017
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181177at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850