Protein Alignment Ac76E and CG32305

DIOPT Version :9

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Alignment Length: 1368
• Identity: 336/1368 - (24%)
• Similarity: 549/1368 - (40%)
• Gaps: 428/1368 - (31%)

  Fly    60 TTAEDI---HLNDLYTRYRQRLRKSLFRSGLLTSLLACVVSIIIGIVYGQHLVQTMLLVLAALIS 121
            :|.:|:   ||.:.....|..|..|..|.   .:|::.||.||..:   :.|:...:::|.||:.
  Fly    19 STVKDLEWRHLKNKCQNLRLELACSRLRE---LALMSNVVQIIWHV---ELLMVAHVILLLALVK 77

  Fly   122 GSILTAL--QFPAVLSSP-----------------------AAALAFAIVTTFSLGTIAAITGDE 161
            ..||..:  .|..:|.||                       |..|....:.:..||||  .:|..
  Fly    78 DIILVTMVPYFAVMLFSPFIMLLSMQNNVGMITNTLISWLMALFLTSMDLVSDLLGTI--YSGAA 140

  Fly   162 LAPLPMY--ALFLCIHSMLPIS-WPVSVVLALFMTAIHIVYRIGTSPDYAPNLPMLFGEI--VML 221
            ...:|.|  .:.:.::..|||: :..|.|..|.| .:.|:| ||    ||..:..|..::  .:|
  Fly   141 YPTVPCYDHVVLVSVYMTLPIAFYQGSSVYVLGM-VVSIIY-IG----YAFYMQYLNDQVSFYLL 199

  Fly   222 ASASVSGL-------YYRIMSDAAHNRTVDGTRTGIEQRVKLECEREQQEQLLLSVIPAYIAAEV 279
            ||.::...       ::.|:.|....|.:......:.|.:..:...:::..||.|::|
  Fly   200 ASYAIYLFTLNLIFSFFTIIRDYGLRRAILSRYQLVYQNIVYQLVMKKENGLLESILP------- 257

  Fly   280 KRSIMLKMADACQRAGGQ---ASTSATRFHELHVQRHTNVTILFADIVNFTPLSSSLTASDLVKT 341
            ::.|.....:.|.|...|   .:.|.....:|.::.:.||:||.||:||:|.|:::|.|..||:.
  Fly   258 RKMIRTLQEEICSRIEDQDKNFTPSKAGLRKLFLEPYPNVSILVADMVNYTHLTTTLEAPQLVEI 322

  Fly   342 LNDLFGRFDQIAQENQCLRIKILGDCYYCVSGLPISRPQHATNCVNMGLQMIDAIRHVREATGIN 406
            |:|||..||..|..|:.:|||.|||.|.||:|:|...|.||:.||:..|:||...:.|.....::
  Fly   323 LHDLFVNFDLAANRNRAMRIKFLGDSYNCVAGIPNYFPAHASCCVDQALEMIHITQGVSSRRELD 387

  Fly   407 VDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGRVHITKQTLDFLGDKFEVEQG 471
            :::|||:|:|.|..|::|..|||||:||.||.:.|.:||.|:.|.||::::||..|.:.:...:|
  Fly   388 INLRIGVHSGEVFAGIIGHTKWQFDIWSKDVDITNRLESSGLPGLVHVSQRTLSMLDEHYIFREG 452

  Fly   472 -EGGNRDAYLADHKVESYLIVPPKPAYTYSVPRVVECIEQNDPSPTTEETKEIKETDQSHEATDV 535
             |....|..|....:.::|:       :..:|..||
  Fly   453 TEAAKNDPILQQAGIRTFLV-------SNRLPDAVE----------------------------- 481

  Fly   536 ADVLLPVTVAPPPAIVDEKMSPTSINSQEAPLHAPLASAASMSIKELSEEEDEADEATAVTEPLM 600
                        |..:|:::|..||||...
  Fly   482 ------------PGELDDELSSASINSCRL----------------------------------- 499

  Fly   601 HRDQDGKNDKEPKANGGHRGSGDSAASESVAKSAALSLPADDLLSMSGSESGISNSGAQAQSSNP 665
                         :.||:
  Fly   500 -------------SYGGY----------------------------------------------- 504

  Fly   666 ASVTPTAAAPAGGAASNSLTVAEAPERSRRKLSVQGLMSFADRRRSSGAFIEGRKLSIHSGESFR 730
                                ..|...:::|:     :|...|:......|||.|:
  Fly   505 --------------------YEEIQIKAQRE-----IMKEVDQMAVGHCFIEWRR---------- 534

  Fly   731 SHAGHVTRNRPSSKMTKYVECWGADRPFANIAESKLVKNIGLASIAMIESNLLPPERKCFNFNFF 795
                       ||.|.|  :.:..:..|:|  :..||..:
  Fly   535 -----------SSSMKK--QDFNEEYLFSN--QIHLVLGV------------------------- 559

  Fly   796 GPPTELKPFTMWYRNTPREAMYRAQPDTHFRFDLICAFVLFLSLAVVQLIVIELN-----LALLG 855
                        :|:..||..:...||...::.::  .||...||::.:.:||..     |.|||
  Fly   560 ------------FRSWKREWEFHNLPDLMIKYTML--LVLCAGLAIMSINLIEEATYPDILVLLG 610

  Fly   856 SLLASFVSLALFLY---------LSNMSVPDVHAS-----TTERNGPGQVVASSRYLRLAMFVVV 906
            .||...:...|..|         |:.||.|....|     .:||      :..|.::|:.:.:||
  Fly   611 ILLILLILCILAGYKKLRLQWKKLTPMSQPSCFLSRWLLRISER------IEDSLFVRIPLTMVV 669

  Fly   907 NILI---SSCAVFSVINYTVPDGVSKEPSSNQTILESNFSSVFVNSTLEDVQLWEIDYAIPIAP- 967
            .:|:   ||.||||.       .|:|...|   |:|::..:             |..||....|
  Fly   670 LLLLYVMSSQAVFSC-------DVAKLELS---IIEAHLYN-------------EKSYAECFGPW 711

  Fly   968 VFLYCCAISLAAISAFLRSGFILKLIAMLVAVIAQVTVLG---------YSDLFEMYNDANITHG 1023
            ...||..|.::.:       |::....:::.::|.:.:||         |...||.....::  |
  Fly   712 TVTYCVVIVISLL-------FVVPGCPLVIKILAGLLILGLHLGTVHLYYGFAFERSETTDL--G 767

  Fly  1024 LPLEI--KGFLLLLVIILVLHTLDRQGEYVARTDFLWKAKL-KVEQEEVETMRGINKILLENILP 1085
            |..:.  ..:|:.|.|:|||.  :|...|:.:.::..:... :..|:..|.:|.| ||::.||||
  Fly   768 LKSDYAHTWYLVALFIVLVLR--ERHVNYLRKFNYFMRVCYEEAHQQTDEKLRSI-KIIMANILP 829

  Fly  1086 AHVATHFLHLERSTELYHESYSCVAVMFASIPNYKEFYDETDVNKQGLECLRLLNEIICDFDKLL 1150
            .|||..:.......:||:|::|.||||||||.|:       :.:..|   ||:|:||||.||.||
  Fly   830 THVAQVYKVRRPHDQLYYENFSKVAVMFASIENF-------NADTAG---LRILHEIICCFDDLL 884

  Fly  1151 L--KPKFSGIEKIKTIASTYMCASGLR-----------PGKEDGATSR-------------SFAD 1189
            :  :.::. |||||.:..|||.|.||.           |.|:..|.|.             |..|
  Fly   885 VDYQTRYK-IEKIKVMGWTYMVACGLETDHYTDFSIDIPVKQPEADSEIRRGSSVLTVHFGSTED 948

  Fly  1190 EK-----------RTEEHNVVILVEFAIALMSILDSI-------NRESFQRFRLRIGLNHGPVIA 1236
            ::           :.::..|:::.|||:.|:.|:..|       ..::|....|:||::||.|:|
  Fly   949 DEMSGDNVSQPYAQVQDVAVLVMTEFALDLLRIMHDIRYNYVFSEYDTFLTGSLKIGISHGSVMA 1013

  Fly  1237 GVIGAQKPQYDIWSNTVNVASRMDSCGVMGRLQTTENTAKILMTAGYECECRGLTYVKGKGNLVT 1301
            ||:|..||.||||.:|||:||||.|.|::..:|.|.:|||:|......|..||.|.|||.|.:.|
  Fly  1014 GVVGLSKPHYDIWGHTVNMASRMSSTGLLDNIQVTRHTAKVLRQFNIRCNYRGHTEVKGVGKVPT 1078

  Fly  1302 YFV 1304
            |.|
  Fly  1079 YLV 1081

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831	55/258 (21%)
		CYCc	259..467	CDD:214485	79/210 (38%)
		Guanylate_cyc	311..469	CDD:278633	69/157 (44%)
		BASP1	510..667	CDD:283191	9/156 (6%)
		CYCc	1079..1283	CDD:214485	88/247 (36%)
		Guanylate_cyc	1101..1305	CDD:278633	92/248 (37%)
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	79/204 (39%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	69/152 (45%)
		CYCc	814..1056	CDD:214485	92/253 (36%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	91/246 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453938
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181177at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850