Protein Alignment Ac76E and gcy-19

DIOPT Version :9

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_001348702.1
• Gene: gcy-19 / 191650
• WormBaseID: WBGene00001544
• Length: 1187
• Species: Caenorhabditis elegans
• Alignment Length: 592
• Identity: 133/592 - (22%)
• Similarity: 224/592 - (37%)
• Gaps: 191/592 - (32%)

  Fly    94 CVV-SIIIGIVYGQHLVQTMLLVLAALISGSILTALQFPAVLSSPAAALAFAIVTTFSLGTIAAI 157
            ||: .:..|:.|   |..:.|.|.|.|.||::|....:.|.|            |.|.|||:|
 Worm   677 CVIRDMAEGLKY---LHNSFLHVHANLRSGTVLVNESWQAKL------------TDFGLGTLA-- 724

  Fly   158 TGDELAPLPMYALFLCIH----SMLPIS-------WPVSVVLALFM-------------TAIHIV 198
              :|..|:....|::...    ::||..       :.::|:.:..:             |...||
 Worm   725 --EEKKPMKRRQLWMAPEVIRGTLLPHQIEKSADIYSLAVIASEVLTRKEAWNMAERKDTVDEIV 787

  Fly   199 YRIGTSPDYAP-------------NLPMLFGEI--------------------VMLASASVSGLY 230
            |||......||             ||.:|..:.                    :|....::....
 Worm   788 YRIKKGGPNAPRPELDMDGVEINHNLLILIRDCWSEEPADRPSADVICNLLKNMMPKKGNLMDHV 852

  Fly   231 YRIMSDAAHNRTVDGTRTGIEQRVK-LECEREQQEQLLLSVIPAYIAAEVKRSIMLKMADACQRA 294
            :.|:.|...|..|:     :|.|.| |..|:::.:.||..::|..:|..:|:
 Worm   853 FNILEDYTTNLEVE-----VEDRTKELTAEKKKADVLLGRMLPKQVAERLKQ------------- 899

  Fly   295 GGQASTSATRFHELHVQRHTNVTILFADIVNFTPLSSSLTASDLVKTLNDLFGRFDQIAQENQCL 359
             ||.         :..:...:||:.|:|:|.||.|::..:...:|..||||:..||.|.:|:.|.
 Worm   900 -GQT---------VEPEGFDSVTVFFSDVVKFTQLAAKCSPFQVVNLLNDLYSNFDAIIEEHGCY 954

  Fly   360 RIKILGDCYYCVSGLPISRPQ-HATNCVNMGLQMID-----AIRHV-REATGINVDMRIGIHTGN 417
            :::.:||.|.||||||..... |....|.:.|..:.     .|.|: ||    .|::|||:::|.
 Worm   955 KVESIGDGYLCVSGLPSKNGNAHIKQIVELSLDFMSYCKSFKIPHLPRE----KVELRIGVNSGP 1015

  Fly   418 VLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGRVHITKQTLDFL-------------GDKFEVE 469
            .:.||:||...::.::.|.|..|:.|||.|.|..:|::..:...|             ||  .:.
 Worm  1016 CVAGVVGLSMPRYCLFGDTVNTASRMESNGKASHIHLSAASYTLLMKHYPNQYNTASRGD--VII 1078

  Fly   470 QGEG-----------------GNRDAYLADHKVESYLIVPPKPAYTYSVPRVVECIEQNDPSPTT 517
            :|:|                 .:...|.:|.|..:....|.      |.|            |:|
 Worm  1079 KGKGVMETFWVFERNNQFMGVSSNSGYQSDKKATNNGSSPE------STP------------PST 1125

  Fly   518 EETKEIKETDQSHEATDVADVLLPVTVAPPPAIVDEKMSPTSINSQEAPLHAPLASAASMSIKEL 582
            ....|:|...             ||....||:.....:|..|:        :|:..|.:   :::
 Worm  1126 PPMHEVKANS-------------PVRHRKPPSPSSPTLSKRSV--------SPIMEAKA---RDI 1166

  Fly   583 SEEEDEA 589
            ..||.||
 Worm  1167 HNEETEA 1173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831	52/253 (21%)
		CYCc	259..467	CDD:214485	63/227 (28%)
		Guanylate_cyc	311..469	CDD:278633	55/177 (31%)
		BASP1	510..667	CDD:283191	16/80 (20%)
		CYCc	1079..1283	CDD:214485
		Guanylate_cyc	1101..1305	CDD:278633
gcy-19	NP_001348702.1	PBP1_NPR_GC_like	45..467	CDD:107347
		PKc_like	571..841	CDD:328722	37/182 (20%)
		CYCc	876..1065	CDD:214485	61/215 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900