Protein Alignment Ac76E and phlp-2

DIOPT Version :9

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: NP_001337270.1
• Gene: phlp-2 / 185690
• WormBaseID: WBGene00009647
• Length: 1126
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 68/410 - (16%)
• Similarity: 131/410 - (31%)
• Gaps: 168/410 - (40%)

  Fly   265 QLLLSVIPAYIAAEVKRSIMLK----MADACQRAGGQASTSATRFHELHVQRHTNVTILFADIVN 325
            :.:.|.:...::.:: |||:|:    :.:..:|.|  ||....|.||..:           :|.:
 Worm   802 RFMTSYLKENVSMDI-RSILLRCHCELGEEGERLG--ASVMIIRVHEKRL-----------EIAS 852

  Fly   326 FTPLSSSLTASDLVKTL--------NDLFGRFDQ----IAQENQCLRIK-ILGDCYYC--VSGLP 375
            ...:|:::..:..:|.:        :|.:.|..:    :.:||   ||. ::|.....  .|..|
 Worm   853 TGTMSAAIARNQKLKMIINGRYEIDDDEYSRIREAHGFVDEEN---RINGVIGSSRQIGHFSTFP 914

  Fly   376 ISRPQHATNCVNMGLQMIDAIRHVREATGINVDMRIGIHTGNVLCGVLGLRKWQFDVWS----DD 436
            :..|.|:...:.:..|:                  .|:..||.:            :|:    ||
 Worm   915 VVLPTHSYRNIQLNEQI------------------EGLIVGNNM------------IWNMLSIDD 949

  Fly   437 V--TLANHMESGGVAGRVHITKQTLDFLGDKFEVEQGEGGNRDAY-------------------- 479
            :  |..|:.....||.::....|:.|:           |||.:..
 Worm   950 LNSTFHNNRSPIVVAKKIQDQLQSYDY-----------GGNSNILVLRRIKPQMTFNGFSTSSTK 1003

  Fly   480 ------LADHKVESYLI--VP--------PKPAYTYSVPRVVECIEQNDPSPTTEETKEIKETDQ 528
                  :|..|::..|:  ||        |.|    .||..:..|....|||
 Worm  1004 NQVTPDIAIPKIDEQLVLAVPALILPEYHPSP----PVPPPIPAIRHRTPSP------------- 1051

  Fly   529 SHEATDVADVLLPVTVAPPPAIVDEKMSPTSINSQEAPLH--APLASAASMSI------------ 579
                             |||.:......|.|...:|..:.  :.|:...::||
 Worm  1052 -----------------PPPPLPSSTPPPVSSEHEEINVRQSSTLSGGYTLSIDRFYSSSSTVSS 1099

  Fly   580 -KELSEEEDEADEATAVTEP 598
             |:.:|..|...::..::.|
 Worm  1100 RKQFNETRDLLSKSLKLSPP 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831	5/27 (19%)
		CYCc	259..467	CDD:214485	39/226 (17%)
		Guanylate_cyc	311..469	CDD:278633	27/178 (15%)
		BASP1	510..667	CDD:283191	16/104 (15%)
		CYCc	1079..1283	CDD:214485
		Guanylate_cyc	1101..1305	CDD:278633
phlp-2	NP_001337270.1	leucine-rich repeat	232..253	CDD:275380
		leucine-rich repeat	254..288	CDD:275380
		PLN00113	283..>718	CDD:331614
		leucine-rich repeat	289..311	CDD:275380
		leucine-rich repeat	312..334	CDD:275380
		leucine-rich repeat	335..357	CDD:275380
		leucine-rich repeat	358..379	CDD:275380
		leucine-rich repeat	380..440	CDD:275380
		leucine-rich repeat	441..485	CDD:275380
		leucine-rich repeat	486..508	CDD:275380
		leucine-rich repeat	509..534	CDD:275380
		leucine-rich repeat	554..577	CDD:275380
		leucine-rich repeat	578..602	CDD:275380
		leucine-rich repeat	603..625	CDD:275380
		leucine-rich repeat	626..649	CDD:275380
		leucine-rich repeat	650..672	CDD:275380
		leucine-rich repeat	673..694	CDD:275380
		PP2Cc	754..985	CDD:214625	42/240 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900