DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ac76E and odr-1

DIOPT Version :9

Sequence 1:	NP_001246838.1	Gene:	Ac76E / 40180	FlyBaseID:	FBgn0004852	Length:	1312	Species:	Drosophila melanogaster
Sequence 2:	NP_001362115.1	Gene:	odr-1 / 181479	WormBaseID:	WBGene00003848	Length:	1047	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	71/238 - (29%)
Similarity:	118/238 - (49%)	Gaps:	29/238 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1068 EVETMRGINKILLENILPAHVATHFLHLERSTELYHESYSCVAVMFASIPNYKEFYDETDVNKQG 1132
            :::|||     ||..:|||.:|.   .|:....:...||....|||..|.::......:...
Worm   805 QMQTMR-----LLNEMLPASIAK---DLKNGLIMPPRSYESATVMFVQICDFNALMKRSSPE--- 858

  Fly  1133 LECLRLLNEIICDFDKLLLKPKFSGIEKIKTIASTYMCASGLRPGKEDGATSRSFADEKRTEEHN 1197
             :.:..||:|...||.::   |.....|::|...|||.|||: |.:.:|......|:
Worm   859 -QVIAFLNDIYDQFDTVI---KRHDAYKVETTGETYMVASGV-PHENEGRHIFEVAE-------- 910

  Fly  1198 VVILVEFAIALMSILDSINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSC 1262
                :...|..:|.:..:..:...:.|:|||.:.||:.|||||.:.|:|.::.:|||.||||.|.
Worm   911 ----ISLEIREISYIYVLQHDKNYKLRIRIGFHAGPIAAGVIGIRSPRYCLFGDTVNFASRMQSN 971

  Fly  1263 GVMGRLQTTENTAKILMTA-GYECECRGLTYVKGKGNLVTYFV 1304
            ....::||:|.||::|..: .|:...||:.:|||||.:..|::
Worm   972 CPPNQIQTSEITARLLFDSHEYKFVKRGIVHVKGKGEVNCYWL 1014

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831
		CYCc	259..467	CDD:214485
		Guanylate_cyc	311..469	CDD:278633
		BASP1	510..667	CDD:283191
		CYCc	1079..1283	CDD:214485	59/204 (29%)
		Guanylate_cyc	1101..1305	CDD:278633	61/205 (30%)
odr-1	NP_001362115.1	Periplasmic_Binding_Protein_type1	63..378	CDD:385651
		PK_GC	495..768	CDD:270894
		CYCc	803..996	CDD:214485	63/218 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910