Protein Alignment Ac76E and AgaP_AGAP004564

DIOPT Version :9

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_313866.5
• Gene: AgaP_AGAP004564 / 1274705
• VectorBaseID: AGAP004564
• Length: 649
• Species: Anopheles gambiae
• Alignment Length: 498
• Identity: 120/498 - (24%)
• Similarity: 209/498 - (41%)
• Gaps: 102/498 - (20%)

  Fly   835 LFLSLAVVQLIV-IELNLALLGSLLASFVSLALFLYLSNMSVPDVHASTTERNGPGQVVASSRYL 898
            |.|:|....||: .|:.:..:|..|           :.:..:.:|:.|.||..| .:|....:..
Mosquito   224 LLLNLFPFALILNEEMKITAVGEKL-----------IESWMLNNVNRSPTELLG-AKVTDHFKLR 276

  Fly   899 RLA--MFVVVNILISSCAVFSVINYTVPDGVSKEPSSNQTIL---ESNFSSVFVNSTLEDVQLWE 958
            |.:  .|...||......:|.:   .:..|.|.:.:.:::.:   :::.|.|..:|:.||..  :
Mosquito   277 RPSGITFTWENIKRLQTVLFEI---QLLKGSSAKGTKDESKIVDTKTSLSQVDTSSSTEDAA--K 336

  Fly   959 IDYAIPIAPVFLYCCAISLAAISAFLRSGFI--LKLIAMLVAVIAQVTVLGYSDLFEM---YNDA 1018
            |..:||         ......:.:.|..|.:  :|.|..||.:.:.: :....:|.||   .||.
Mosquito   337 IMTSIP---------RRGSQGLRSILLKGEMRYIKDINSLVFLCSPL-INNLEELREMGLYLNDL 391

  Fly  1019 NITHGLPLEI--KGFLLLLVIILVLHTLDRQGEYVARTDFLWKAKLKVEQ--EEVETMRGI---- 1075
            | .|||..|:  .||                 .:.:|.|.:.:   :.||  ||:||...:
Mosquito   392 N-PHGLSREMVFSGF-----------------SHYSRLDLMCE---REEQRAEELETSLALADSW 435

  Fly  1076 ---NKILLENILPAHVATHFLHLERSTELYHE---SYSCVAVMFASIPNYKEFYDETDVNKQGLE 1134
               ...||.:::|..:|...    |..:..||   |:..|.|:||.:   :|.....|..|..:.
Mosquito   436 KRQGDELLYSMIPRSIAERL----REGQNPHETCQSFEEVTVLFAEV---QETITGDDSIKYAMT 493

  Fly  1135 CLRLLNEIICDFDKLLLKPKFSGIEKIKTIASTYMCASGLRPGKEDGATSRSFADEKRTEEHNVV 1199
            .:..||.....||:|:..|.   ..|::|:...||..||                   ..:.|..
Mosquito   494 TVNTLNAAFSAFDELIHSPM---AYKVETVGKVYMAVSG-------------------APDINPF 536

  Fly  1200 ILVEFAIALMSILDSINRESFQRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCGV 1264
            .....|...:.:|.||.:.:.....::||.:.||::||::|.:.|:|.::.:|||.||||:|.|.
Mosquito   537 HAQHMADLALDMLHSIRQLNLPGVGVKIGFHSGPIVAGIVGLKVPRYCLFGDTVNTASRMESSGE 601

  Fly  1265 MGRLQTTENTAKILMTAGYECECRGLTYVKGKGNLVTYFVKTP 1307
            ...:|.:..||:.|...||....||...|||||::.|::::.|
Mosquito   602 TDCIQVSGYTAQKLKKLGYVLAYRGKVAVKGKGDMETFWLQGP 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831
		CYCc	259..467	CDD:214485
		Guanylate_cyc	311..469	CDD:278633
		BASP1	510..667	CDD:283191
		CYCc	1079..1283	CDD:214485	54/206 (26%)
		Guanylate_cyc	1101..1305	CDD:278633	59/206 (29%)
AgaP_AGAP004564	XP_313866.5	HNOB	2..164	CDD:285002
		HNOBA	219..455	CDD:285003	59/278 (21%)
		CYCc	436..620	CDD:214485	54/212 (25%)
		Guanylate_cyc	466..643	CDD:278633	57/201 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810