Protein Alignment Ac76E and AgaP_AGAP004555

DIOPT Version :9

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_313853.4
• Gene: AgaP_AGAP004555 / 1274696
• VectorBaseID: AGAP004555
• Length: 720
• Species: Anopheles gambiae
• Alignment Length: 579
• Identity: 130/579 - (22%)
• Similarity: 233/579 - (40%)
• Gaps: 131/579 - (22%)

  Fly     2 VNHNAETAKTGNGT-------NATANLI--VKADGNATQPKAMTSSAARMNDALSASLADL---- 53
            ::.|.|.|.|.|.|       |...:|:  :....|.||   :..|....||||:....||
Mosquito   184 ISANEEMALTINITRLLNVIQNERMSLVFYMLTGKNRTQ---VELSIEHTNDALNHLGEDLNYLL 245

  Fly    54 -SEQENGTTAEDIHL----NDLYTRYRQRLRKSLFRSGLLTSLLACVVSIIIGIVYGQHLVQTML 113
             :...|.|...|:.:    |:.:|........:.....::..::....:.|...|:.|.:|...|
Mosquito   246 PAGTANHTLIADMRIKTPENETFTGLEYFEPYNALNRYVINQIVRSTGTSISSTVWRQFVVYKNL 310

  Fly   114 LVLAALISGSILTALQF-----------PAVLSSPAAALAFAIVTTFSLGTIAAITGDELAPLPM 167
            :.....|:.:.:..|||           ...:...||||.:.......:.:::.|:..|.:.:..
Mosquito   311 IEAIESINIAAILVLQFICNGYLGLSDYAQFIRRDAAALDYIASAQNFMTSLSIISEAEFSAMQY 375

  Fly   168 Y---------------ALFLCIHSMLPISWPVSVVLALFMTAI-------------HIVYRIGTS 204
            :               ||....||:..:...:.:|.....|.:             |....||.
Mosquito   376 WRTQVLINISTGYRRDALVEYYHSVTTVLKNLQMVQDQIQTDVKETILEEIQSARRHQSISIGL- 439

  Fly   205 PDYAPNLPMLFGEIVMLASASVSGLYYRIMSDAAHNRTVDGTRTGIEQR-VKLECEREQQEQLLL 268
                        .:|:|..:.:..|..|     |...|:....|.:..| ::|..|:.:.::||.
Mosquito   440 ------------VVVILIISPILVLMIR-----AATSTIQNYSTKLMARTMELRMEKGKSDRLLY 487

  Fly   269 SVIPAYIAAEVK--RSIMLKMADACQRAGGQASTSATRFHELHVQRHTNVTILFADIVNFTPLSS 331
            .::|..:..::|  |.:..:..||                         |||.|:|||.||.:|:
Mosquito   488 QMLPPAVVKQLKQQRQVPAETFDA-------------------------VTIFFSDIVGFTDISA 527

  Fly   332 SLTASDLVKTLNDLFGRFDQIAQENQCLRIKILGDCYYCVSGLP-ISRPQHATNCVNMGLQMIDA 395
            |.:|.::|..||.|:..||.|..:....:::.:||.|..||||| .:..:||.....|.|.::..
Mosquito   528 SSSAMEVVIMLNTLYRLFDSIILKYDVYKVETIGDAYMVVSGLPQRNGNRHAGEIAMMSLDLVCG 592

  Fly   396 IR-----HVREATGINVDMRIGIHTGNVLCGVLGLRKWQFDVWSDDVTLANHMESGGVAGRVHI- 454
            |.     |::..|   :::|:||:||..:.||:|....::.::.|.:..|:.|||.|...::||
Mosquito   593 ISGFTIPHMKNRT---LEIRVGINTGPCVAGVVGTTMPRYCLFGDTINTASRMESTGEPMKIHIS 654

  Fly   455 --TKQTLDFLGDKFEVE-------QGEGGNRDAYLADHKVESYLIVPPK---PAYTYSV 501
              ||:.||.||. |:::       :|:|..:..:|..|.:..:|  .|:   |.|..:|
Mosquito   655 ESTKEVLDKLGG-FKIKLRGTVDVKGKGTMQTFWLTGHSMYEHL--TPEMLIPMYKQNV 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831	41/267 (15%)
		CYCc	259..467	CDD:214485	64/218 (29%)
		Guanylate_cyc	311..469	CDD:278633	57/166 (34%)
		BASP1	510..667	CDD:283191
		CYCc	1079..1283	CDD:214485
		Guanylate_cyc	1101..1305	CDD:278633
AgaP_AGAP004555	XP_313853.4	NIT	<267..414	CDD:285564	21/146 (14%)
		HNOBA	<466..498	CDD:285003	7/31 (23%)
		CYCc	477..666	CDD:214485	63/216 (29%)
		Guanylate_cyc	504..690	CDD:278633	62/214 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810