Protein Alignment Ac76E and npr3

DIOPT Version :10

• Sequence 1: NP_001246838.1
• Gene: Ac76E / 40180
• FlyBaseID: FBgn0004852
• Length: 1312
• Species: Drosophila melanogaster
• Sequence 2: XP_004910476.1
• Gene: npr3 / 100495974
• XenbaseID: XB-GENE-1012470
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 562
• Identity: 111/562 - (19%)
• Similarity: 181/562 - (32%)
• Gaps: 209/562 - (37%)

  Fly     9 AKTGNGTNATANLIVKADGNATQPK--AMTSSAARMNDALSASLADLSEQENGTTAEDIHLNDLY 71
            ||:......|.|::|      ..||  :...|..|:..|:..:|..:  |||.|....:|.|.:|
 Frog    17 AKSNPVDEDTVNMLV------LLPKDNSYMFSMDRVRPAVDHALRSI--QENQTLLPGMHFNVIY 73

  Fly    72 TRYRQRLRKSLFRSGLLTSLLACVVSIIIGIVYGQHLVQTMLLVLAALISGSILTALQFPAVLSS 136
                   ..|...:..|.||:                              .|...||.|.|:..
 Frog    74 -------NDSDCGNQALFSLI------------------------------DIAMQLQKPDVILG 101

  Fly   137 PAAALAFAIVT---------TFSLGTIA---AITGDELAPL----PMYA----LFLCI---HSML 178
            |....|.|.|.         ..|.|.:|   ....:|.:.|    |:|:    :||.:   |
 Frog   102 PVCEYAAAPVARLASHWNVPMLSAGALAIGFMQKSNEYSHLTRVSPVYSKMGEMFLAMFRYH--- 163

  Fly   179 PISWPVSVVL--------ALFMT--AIHIVYRIGTSPDYAPNLPMLFGE---------------- 217
              .|..:.:|        ..|.|  .:|:.::   ...||.::.. |.|
 Frog   164 --KWTKAFLLYTDDNLQRNCFFTLEGVHLAFK---EEGYAMSIHN-FDETKHVDAEEIVHSIQNK 222

  Fly   218 ---IVMLASASVSGLYYRIMSDAAHNRTVDGTRTG------IE---------------QRVKLEC 258
               ::|.||:..    .|.:..|||.:   |...|      ||               .:..||.
 Frog   223 ERVVIMCASSDT----VRNIMLAAHRQ---GMTNGDYVFFNIELFNSSTYGNGSWKRGDKYDLEA 280

  Fly   259 ERE----QQEQLLLSVIPAY--IAAEVKRSIMLKMADACQRAGGQASTSATRFHELHVQRHTNVT 317
            ::.    |...||.:|.|.:  .:.|||.|:        |:.|    .:...:..:.|:...:..
 Frog   281 KQAYSSLQTVTLLRTVKPEFEKFSMEVKSSV--------QKLG----LNEDDYVNMFVEGFHDAI 333

  Fly   318 ILFADIVNFTPLSSSLTASD---LVKTL-----------------NDLFGRFDQIAQ-ENQCLRI 361
            ||:| :.....|.:..:..|   ||:.:                 .|.:|.|..||. :.:....
 Frog   334 ILYA-LALHELLKNGFSKKDGEKLVQQMWNRTYEGIAGQVSIDANGDRYGDFSVIAMTDKETGTQ 397

  Fly   362 KILGDCYYCVSGLPISRP------------------QH--ATNCVNMGLQMIDAIRHVREATGIN 406
            :::|| ||.:.|....||                  :|  .|.|.:.|.....|:      |||.
 Frog   398 EVIGD-YYGIQGHFEIRPNVKPPWGPGRLLINERIVEHPSTTPCKSSGGLGESAV------TGIV 455

  Fly   407 VDMRIGIHTGNVLCGVLGLRKWQFDV----WSDDVTLANHME 444
            |...:|  ||.::......:|::..:    ..||..|..|.:
 Frog   456 VGAFLG--TGLLMAFYFFRKKYRITIERRNQQDDCNLGKHRQ 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ac76E	NP_001246838.1	AcyC	72..470	CDD:441717	93/497 (19%)
		Guanylate_cyc	310..469	CDD:425528	37/180 (21%)
		Guanylate_cyc	1101..1305	CDD:425528
npr3	XP_004910476.1	PBP1_NPR_C	25..414	CDD:380609	90/463 (19%)