DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGDI and arhgdib

DIOPT Version :9

Sequence 1:	NP_001262080.1	Gene:	RhoGDI / 40179	FlyBaseID:	FBgn0036921	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_001006838.1	Gene:	arhgdib / 448583	XenbaseID:	XB-GENE-943891	Length:	200	Species:	Xenopus tropicalis

Alignment Length:	202	Identity:	96/202 - (47%)
Similarity:	129/202 - (63%)	Gaps:	6/202 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAETETKHHPEHHDDDVH-DANYQAPPEKTIEEIMAADQEDESLRRYKEALLGAAQTEKIIVEPN 64
            |.|.|...|....||::. ..||:.||:|:::||...|::||||.:||::|||..   .:..:|:
Frog     1 MTENEPVPHDVEDDDELDGKLNYKPPPQKSLQEIQELDKDDESLAKYKKSLLGDG---PVAADPS 62

  Fly    65 DPRKVIVKKLALVVEGRDDM-ELDLTGDLSQLKKQLFVIKEGVQYKVRIDFIVQREIVHGLKYVQ 128
            .| .|||.:|.||......: .:||||||:.|||:.|.:||||:|:|:|.|.|.:|||.||||.|
Frog    63 AP-NVIVTRLTLVCATAPKLITMDLTGDLTNLKKETFALKEGVEYRVKIHFKVTKEIVSGLKYDQ 126

  Fly   129 KTSRLGVNVDKMKHMVGSYPPKKEIQFYLTPAEEAPSGTFSRGTYSVSSVFTDDDKHIHLEWDWT 193
            ...|.||.|.|.:.|||||.|::|...:|||.||||.|..:||||...|.|||||.|.||.|:|.
Frog   127 YIYRAGVRVTKARFMVGSYGPRQEEYEFLTPLEEAPKGILARGTYLNKSHFTDDDNHNHLSWEWN 191

  Fly   194 FEIKKDW 200
            ..|:|:|
Frog   192 LTIRKEW 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGDI	NP_001262080.1	Rho_GDI	14..199	CDD:280310	90/186 (48%)
arhgdib	NP_001006838.1	Rho_GDI	8..197	CDD:366924	91/192 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	174	1.000	Domainoid score	I3621
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3861
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1265661at2759
OrthoFinder	1	1.000	-	-		FOG0001289
OrthoInspector	1	1.000	-	-		otm47458
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2126
SonicParanoid	1	1.000	-	-		X792
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.090