DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8004 and Mtx2

DIOPT Version :9

Sequence 1:	NP_649161.1	Gene:	CG8004 / 40178	FlyBaseID:	FBgn0036920	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_058084.3	Gene:	Mtx2 / 53375	MGIID:	1859652	Length:	263	Species:	Mus musculus

Alignment Length:	259	Identity:	110/259 - (42%)
Similarity:	164/259 - (63%)	Gaps:	11/259 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YLSQLITADKLSAEPWPEDATLYQPYEAEQILLPENASCLAVKAYLKMCNLPFLIRSCANAEHMS 69
            ::||:     .:.|||||:|||||....|||||.:||:.|||:|:|:|||||..:...||||:||
Mouse     8 FVSQI-----AATEPWPENATLYQQLRGEQILLSDNAASLAVQAFLQMCNLPVKVVCRANAEYMS 67

  Fly    70 PGGRMTKLPFIRAGAFIFAEFEPIVNFVEQKELAIGSWQDEDEKADMRTYVSLVENIFTMAELYI 134
            |.|   |:|||..|..:.:|..|||.||:.|..::....||.:||:|:.|:.||.|:...||||:
Mouse    68 PSG---KVPFIHVGNQVVSELGPIVQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYL 129

  Fly   135 SFKNERVYKEVTAPRNGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVIDKVAKCCETLE 199
            .:.:|....|:|..|.|..:||||||:..|.|:....|.:|...|.:..:|.|::.|.:||:.|.
Mouse   130 QWCDEATVGEITIARYGSPYPWPLNHILAYQKQWEVKRKMKAIGWGNKTLDQVLEDVDQCCQALS 194

  Fly   200 YKLKESPETPFFYGDQPCELDAIAFGHLFSILTTTLPNMALAQTVQKFQHLVEFCRFVDEKYFQ 263
            .:|...   |:|:..||.||||:.||||::||||.|.:..|::.|:.:.:|:.|||.:::.||:
Mouse   195 QRLGTQ---PYFFNKQPTELDALVFGHLYTILTTQLTSDELSEKVKNYSNLLAFCRRIEQHYFE 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8004	NP_649161.1	GST_N_Metaxin2	24..100	CDD:239377	41/75 (55%)
CG8004	NP_649161.1	GST_C_Metaxin2	130..258	CDD:198320	50/127 (39%)
Mtx2	NP_058084.3	GST_N_Metaxin2	22..95	CDD:239377	41/75 (55%)
		GstA	33..252	CDD:223698	94/224 (42%)
		GST_C_Metaxin2	125..250	CDD:198320	50/127 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849471
Domainoid	1	1.000	110	1.000	Domainoid score	I6328
eggNOG	1	0.900	-	-		E1_KOG3027
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4777
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3547
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52965
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005469
OrthoInspector	1	1.000	-	-		otm42663
orthoMCL	1	0.900	-	-		OOG6_105112
Panther	1	1.100	-	-	LDO	PTHR12289
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2657
SonicParanoid	1	1.000	-	-		X3890
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790