DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8004 and mtx2

DIOPT Version :9

Sequence 1:	NP_649161.1	Gene:	CG8004 / 40178	FlyBaseID:	FBgn0036920	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001004770.1	Gene:	mtx2 / 447951	XenbaseID:	XB-GENE-943941	Length:	274	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	110/263 - (41%)
Similarity:	165/263 - (62%)	Gaps:	11/263 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTSQYLSQLITADKLSAEPWPEDATLYQPYEAEQILLPENASCLAVKAYLKMCNLPFLIRSCANA 65
            :|..::||:     .:.|||||:|.||||.::||:||.:|||||||:|:|||||||..:...|||
Frog     4 VTDAFVSQI-----AAVEPWPENAALYQPLKSEQVLLSDNASCLAVQAFLKMCNLPVQVVCRANA 63

  Fly    66 EHMSPGGRMTKLPFIRAGAFIFAEFEPIVNFVEQKELAIGSWQDEDEKADMRTYVSLVENIFTMA 130
            |:|||.|   |:|||..|..:.:|..|||.||:.|..::....||.::|:|:.|:.||.|:...|
Frog    64 EYMSPSG---KVPFIHVGNQVISELGPIVQFVKAKGHSLSDGLDEVQRAEMKAYMELVNNMLLTA 125

  Fly   131 ELYISFKNERVYKEVTAPRNGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVIDKVAKCC 195
            ||||.:.:|...:|:|.||....:.||||:...:.::....|.:|...|....::.|.:.|.:||
Frog   126 ELYIQWCDEATLEEITQPRYSFPYSWPLNYFLVFQRKWEIKRKMKAIGWATKTLEQVFEDVDQCC 190

  Fly   196 ETLEYKLKESPETPFFYGDQPCELDAIAFGHLFSILTTTLPNMALAQTVQKFQHLVEFCRFVDEK 260
            :.|..:|...   |:|:..||.||||:.|||||:||||.|.|..|.:.|:.:.:|:.|||.:::.
Frog   191 QALSQRLGTQ---PYFFNKQPTELDALVFGHLFTILTTQLTNDELQEKVKNYSNLIAFCRRIEQH 252

  Fly   261 YFQ 263
            ||:
Frog   253 YFE 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8004	NP_649161.1	GST_N_Metaxin2	24..100	CDD:239377	43/75 (57%)
CG8004	NP_649161.1	GST_C_Metaxin2	130..258	CDD:198320	48/127 (38%)
mtx2	NP_001004770.1	GST_N_Metaxin2	22..95	CDD:239377	43/75 (57%)
mtx2	NP_001004770.1	GST_C_Metaxin2	125..250	CDD:198320	48/127 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	109	1.000	Domainoid score	I6286
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4777
Inparanoid	1	1.050	169	1.000	Inparanoid score	I4021
OMA	1	1.010	-	-		QHG52965
OrthoDB	1	1.010	-	-		D1219712at2759
OrthoFinder	1	1.000	-	-		FOG0005469
OrthoInspector	1	1.000	-	-		otm47765
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2657
SonicParanoid	1	1.000	-	-		X3890
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.010