DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8004 and Mtx2

DIOPT Version :9

Sequence 1:	NP_649161.1	Gene:	CG8004 / 40178	FlyBaseID:	FBgn0036920	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001008287.1	Gene:	Mtx2 / 288150	RGDID:	1306473	Length:	263	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	108/261 - (41%)
Similarity:	162/261 - (62%)	Gaps:	11/261 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YLSQLITADKLSAEPWPEDATLYQPYEAEQILLPENASCLAVKAYLKMCNLPFLIRSCANAEHMS 69
            ::||:     .:.|||||:|||||....|||||.:||:.|||:.:|:|||||..:...||||:||
  Rat     8 FVSQI-----AATEPWPENATLYQQLRGEQILLSDNAASLAVQTFLQMCNLPVKVVCRANAEYMS 67

  Fly    70 PGGRMTKLPFIRAGAFIFAEFEPIVNFVEQKELAIGSWQDEDEKADMRTYVSLVENIFTMAELYI 134
            |.|   |:|||..|..:.:|..||:.||:.|..::....||.:||:|:.|:.||.|:...||||:
  Rat    68 PSG---KVPFIHVGNQVVSELGPIIQFVKAKGHSLSDGLDEVQKAEMKAYMELVNNMLLTAELYL 129

  Fly   135 SFKNERVYKEVTAPRNGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVIDKVAKCCETLE 199
            .:.:|....|:|..|.|..:|||||.:..|.|:....|.:|...|.:..:|.|::.|.:||:.|.
  Rat   130 QWCDEATVGEITLARYGSPYPWPLNLILTYQKQCEVKRKMKAIGWGNKTLDQVLEDVDRCCQALS 194

  Fly   200 YKLKESPETPFFYGDQPCELDAIAFGHLFSILTTTLPNMALAQTVQKFQHLVEFCRFVDEKYFQT 264
            .:|...   |:|:..||.||||:.||||::||||.|.:..|.:.|:.:.:|:.|||.:::.||:.
  Rat   195 QRLGTQ---PYFFDKQPTELDALVFGHLYTILTTQLTSDELCEKVKNYSNLLAFCRRIEQDYFED 256

  Fly   265 R 265
            |
  Rat   257 R 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8004	NP_649161.1	GST_N_Metaxin2	24..100	CDD:239377	39/75 (52%)
CG8004	NP_649161.1	GST_C_Metaxin2	130..258	CDD:198320	49/127 (39%)
Mtx2	NP_001008287.1	GST_N_Metaxin2	22..95	CDD:239377	39/75 (52%)
		GstA	33..251	CDD:223698	91/223 (41%)
		GST_C_Metaxin2	125..250	CDD:198320	49/127 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353112
Domainoid	1	1.000	104	1.000	Domainoid score	I6565
eggNOG	1	0.900	-	-		E1_KOG3027
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4777
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3535
OMA	1	1.010	-	-		QHG52965
OrthoDB	1	1.010	-	-		D1219712at2759
OrthoFinder	1	1.000	-	-		FOG0005469
OrthoInspector	1	1.000	-	-		otm44729
orthoMCL	1	0.900	-	-		OOG6_105112
Panther	1	1.100	-	-	LDO	PTHR12289
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3890
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770