DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8004 and wdr86

DIOPT Version :9

Sequence 1:	NP_649161.1	Gene:	CG8004 / 40178	FlyBaseID:	FBgn0036920	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	XP_002932539.2	Gene:	wdr86 / 100486668	XenbaseID:	XB-GENE-981853	Length:	415	Species:	Xenopus tropicalis

Alignment Length:	185	Identity:	31/185 - (16%)
Similarity:	55/185 - (29%)	Gaps:	35/185 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 FAEFEPIVNFVEQKELAIGSWQDEDEKADM--RTYVSLVENIFTMAELYISFKNERVYKEVTAPR 149
            |...|....|....:..:..|:....:..|  ..:.|:|..|........|...:|..:...|..
Frog    84 FCHLENEAAFTCSADQTVRKWEVSSGECVMVYTGHTSIVNRILVAKGYIFSGSYDRTARSWNADS 148

  Fly   150 NGVVFPWPLNHMQNYGKRRNALRLLKVYQWDDLDIDSVIDKVAKCCETLEYKLKESPE--TPFFY 212
            .        ..:|.:...||.  :|.:..:...|:...:|...|  |..|:.:..|.:  ...:.
Frog   149 G--------QSLQEFRGHRNC--VLTLAHFSSYDVLEALDVEEK--EVKEFLVTGSTDCTIKIWE 201

  Fly   213 GDQPCELDAIAFGHLFSILTTTLP------------------NMALAQTVQKFQH 249
            ....|....:. ||:.:||...|.                  ||.....:..|:|
Frog   202 ASSGCCYQTLR-GHVGAILCVVLDTSNGELYSGSMDCTIRRWNMVTGDQLTVFRH 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8004	NP_649161.1	GST_N_Metaxin2	24..100	CDD:239377	3/12 (25%)
CG8004	NP_649161.1	GST_C_Metaxin2	130..258	CDD:198320	23/140 (16%)
wdr86	XP_002932539.2	WD40	29..320	CDD:238121	31/185 (17%)
		WD40 repeat	41..77	CDD:293791
		WD40 repeat	123..157	CDD:293791	5/41 (12%)
		WD40 repeat	162..212	CDD:293791	8/51 (16%)
		WD40 repeat	219..254	CDD:293791	4/34 (12%)
		WD40 repeat	260..294	CDD:293791
		WD40 repeat	300..333	CDD:293791
		WD40	326..363	CDD:197651
		WD40 repeat	340..362	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910