Protein Alignment Grasp65 and GORASP1

DIOPT Version :9

• Sequence 1: NP_649160.1
• Gene: Grasp65 / 40177
• FlyBaseID: FBgn0036919
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: XP_006713364.1
• Gene: GORASP1 / 64689
• HGNCID: 16769
• Length: 445
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 171/448 - (38%)
• Similarity: 235/448 - (52%)
• Gaps: 74/448 - (16%)

  Fly    21 KVQDNSPGQKAGLEAFFDFIVAIAGTRLDQDNDMLKELLRQNVDKPVRLTVYSSKTQTVRELTLT 85
            :||:|||.|:||||.:||||:.|..:||:::||.||.||:.||:|||:|.|::.||..|||:.:.
Human    26 QVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVV 90

  Fly    86 PSNNWGGQGLLGVSIRFCSFEGANESVWHILEVHPNSPAELAGLRAYSDYVIGADAIRHENDDLF 150
            |||.||||||||.|:|||||..|:|.|||:|:|.|:|||.|||||.|:|||:|:|.|..|::|.|
Human    91 PSNMWGGQGLLGASVRFCSFRRASEQVWHVLDVEPSSPAALAGLRPYTDYVVGSDQILQESEDFF 155

  Fly   151 TLIETHEQQPLKMYVYNLDDDACREVTIKPNTAWGGEGALGCGIGFGYLHRIPVQAEPVTSSSAA 215
            ||||:||.:|||:.|||...|:|||||:.||.||||||:||||||:|||||||.|    ..|...
Human   156 TLIESHEGKPLKLMVYNSKSDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQ----PPSYHK 216

  Fly   216 VPAAAAAESTAPLLTAGGAAPAGAQVAQVVSPTLPYIPPLANTFGSTNAEVRPPTIEPPAQSLFK 280
            .|......|..||    ||.|..|            :||     |.|..:  .|::|..::.
Human   217 KPPGTPPPSALPL----GAPPPDA------------LPP-----GPTPED--SPSLETGSRQ--- 255

  Fly   281 TYFNPDEATDALTAALESQ-ATIAEPVSVPAPPAVADVSVAQPQVQ-----VPAPAQPLPPPANI 339
                    :|.:.|.|::. :::.:|:..|..|     |.:.|...     :..|.||.||...:
Human   256 --------SDYMEALLQAPGSSMEDPLPGPGSP-----SHSAPDPDGLPHFMETPLQPPPPVQRV 307

  Fly   340 FIPGVFDP---STQQNANALGGIPAAQLPFPQATAAPAAVPMFSAPQQAYMSAPAALSYPAGAQT 401
            ..||..|.   |...|:||     :.....|.:|.........|.|:....|:.   |:..|.:.
Human   308 MDPGFLDVSGISLLDNSNA-----SVWPSLPSSTELTTTAVSTSGPEDICSSSS---SHERGGEA 364

  Fly   402 VPSYPQVQPSM----GGLFPTQPTP---LPPQMAHVFAPP-------VPPQAGAAPAA 445
            ..|..:.:.|.    |........|   ||..:....:|.       :..||...||:
Human   365 TWSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPEDGLSAELLEAQAEEEPAS 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grasp65	NP_649160.1	PDZ	<14..100	CDD:294084	46/78 (59%)
		GRASP55_65	69..205	CDD:282364	89/135 (66%)
GORASP1	XP_006713364.1	PDZ	<26..105	CDD:294084	46/78 (59%)
		GRASP55_65	74..210	CDD:282364	89/135 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158789
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5233
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1366434at2759
OrthoFinder	1	1.000	-	-		FOG0002082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102404
Panther	1	1.100	-	-	LDO	PTHR12893
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1703
SonicParanoid	1	1.000	-	-		X1377
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.780