Protein Alignment Grasp65 and gorasp2

DIOPT Version :10

• Sequence 1: NP_649160.1
• Gene: Grasp65 / 40177
• FlyBaseID: FBgn0036919
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001004798.1
• Gene: gorasp2 / 448025
• XenbaseID: XB-GENE-943266
• Length: 423
• Species: Xenopus tropicalis
• Alignment Length: 467
• Identity: 206/467 - (44%)
• Similarity: 261/467 - (55%)
• Gaps: 102/467 - (21%)

  Fly     1 MGSSHSIHVPGGGTEGYHVLKVQDNSPGQKAGLEAFFDFIVAIAGTRLDQDNDMLKELLRQNVDK 65
            ||.|:|:.:|||||||||||:||:||||.:||||.||||||:|.|.||::|||.||:||:.||:|
 Frog     1 MGGSNSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSINGIRLNKDNDTLKDLLKANVEK 65

  Fly    66 PVRLTVYSSKTQTVRELTLTPSNNWGGQGLLGVSIRFCSFEGANESVWHILEVHPNSPAELAGLR 130
            ||::.||||||..:||.::||||.|||||||||||||||||||||:|||:|||.|||||.|||||
 Frog    66 PVKMVVYSSKTLELRETSVTPSNMWGGQGLLGVSIRFCSFEGANENVWHVLEVEPNSPAALAGLR 130

  Fly   131 AYSDYVIGADAIRHENDDLFTLIETHEQQPLKMYVYNLDDDACREVTIKPNTAWGGEGALGCGIG 195
            |:|||:||||.:.:|::|||:||||||.:|||:||||.|.|.||||.|.|||||||||:||||||
 Frog   131 AHSDYIIGADTVMNESEDLFSLIETHEGKPLKLYVYNTDTDNCREVVITPNTAWGGEGSLGCGIG 195

  Fly   196 FGYLHRIPVQ------------------AEPVTSSSAAVPAAAAAESTAPLLTAG-GAAPAGAQV 241
            :|||||||.:                  ..|:......|..:..:..|.||.||| .|:.:|..:
 Frog   196 YGYLHRIPTRPFEEGKNISMPGQVPGAPVSPLKDGFTEVQLSVNSPPTLPLGTAGIEASMSGLSI 260

  Fly   242 ---AQVVS-------PTLPYIPPLANTFGSTNAEVRPPTIEPPAQSLFKTYFNPDEATDALTAAL 296
               :.|||       ||:|.|.|..|           |::.|.|       .||
 Frog   261 GASSPVVSSAINAGLPTVPVITPQIN-----------PSLAPVA-------LNP----------- 296

  Fly   297 ESQATIAEPVSVPAPPAVADVSVAQPQVQVPAPAQPLPPPANIFIPGVFDPSTQQNANALGGIPA 361
                    .||:   |::..:|...|.:|.......:..||...||....|...|   |:.|:|.
 Frog   297 --------AVSL---PSIMPLSTGLPHLQNLPNLPNINMPAPHLIPRTGLPDLSQ---AVAGLPP 347

  Fly   362 AQLPFPQATAAPAAVPMFSAPQQAYMSAPAALSYPAGAQTVPSYPQVQPSMGGLFPTQPTP---- 422
            .. |.|....  ..:|....|.|                 .|::| :.|.:|.:    |.|
 Frog   348 LG-PLPHLNL--TGMPPLPVPSQ-----------------FPAFP-LAPMVGDI----PPPLLDH 387

  Fly   423 -LPPQMAHVFAP 433
             |.|...||.||
 Frog   388 SLAPTTEHVTAP 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Grasp65	NP_649160.1	PDZ_canonical	<14..100	CDD:483948	60/85 (71%)
		GRASP55_65	69..205	CDD:427981	103/135 (76%)
gorasp2	NP_001004798.1	PDZ_canonical	<14..100	CDD:483948	60/85 (71%)
		GRASP55_65	69..204	CDD:427981	102/134 (76%)
		Atrophin-1	254..>410	CDD:460830	47/214 (22%)