Protein Alignment Rpn1 and psmd2

DIOPT Version :10

• Sequence 1: NP_649158.1
• Gene: Rpn1 / 40174
• FlyBaseID: FBgn0028695
• Length: 919
• Species: Drosophila melanogaster
• Sequence 2: NP_001015819.1
• Gene: psmd2 / 548536
• XenbaseID: XB-GENE-972398
• Length: 897
• Species: Xenopus tropicalis
• Alignment Length: 913
• Identity: 564/913 - (61%)
• Similarity: 723/913 - (79%)
• Gaps: 23/913 - (2%)

  Fly     8 EKKPLKPAASEGDAKDPKAKKDEKKDGKDKEQQPELSDEDQQLQEELELLVQHLQEPDAKLYQPT 72
            |:...:.|...|..||.:|..:::...|||::..|||:||:|||:|||:||:.|.|.|:.||:|.
 Frog     3 EQSRNQQALQTGKGKDKEAGGEQRDAAKDKKEDQELSEEDKQLQDELEMLVERLGEKDSSLYRPA 67

  Fly    73 LESMAKLIRASTTSMTSVPKPLKFMRPHYETMKTVYKHMPNEQARQLCADIISVLSMTMGSGKDC 137
            ||.:.:.||:||||||||||||||:||||..:|.:|::|...:.:|..|||||||:|||.|.::|
 Frog    68 LEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKQFAADIISVLAMTMSSEREC 132

  Fly   138 LAYRFLCDRKQRIGDWGHEYVRHLSGEISAHYHDTTGDFRVQ---LIELVKQIIPYNMEHNAEAD 199
            |.||.| ..::.:..|||||||||:||::..:.:.....:.|   |:.|||:|:||||.||||.:
 Frog   133 LKYRLL-GSQEELASWGHEYVRHLAGEVAKEWQEVEEGDKSQKDTLLTLVKEIVPYNMAHNAEHE 196

  Fly   200 ACDLLIEIDHLHLLSDFVDESAYPRVCLYLQSCYPYVPDPDNTIILETALQLSRKFNQYTQAMRL 264
            |||||:||:.:.:|..::|::||.:|||||.||..|||:|:|:.:|..||.:.||||:|.:|:||
 Frog   197 ACDLLMEIEQMDMLEKYIDDNAYAKVCLYLTSCVSYVPEPENSALLRCALSIFRKFNRYPEALRL 261

  Fly   265 ALMLNDMDKIGEIFKEPKEPAMQKQLAFMLARQQICLELDELVPDYDDLMEIMSNANLNKHFLNL 329
            ||:||||:.:.:||...|:..:|||::|||.|..:.|.|:|.|.:|:||.|||||..||.:||.|
 Frog   262 ALVLNDMELVEDIFTSCKDVVVQKQMSFMLGRHGVYLALNEDVEEYEDLTEIMSNVQLNSNFLAL 326

  Fly   330 ARELDIMEPKTPEDIYKSHLDNSRSRFASIQVDSAKQNLAASFVNGFVNAGFGVDKLLSEDGNKW 394
            ||||||||||.|:||||:||:|:|...:..|||||:.|||:|||||||||.||.||||::|||||
 Frog   327 ARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKW 391

  Fly   395 LYKNKEHGMLSATASLGLILLWDVDGGLTMIDKYLYSTDDNIKSGALLACGIVNCGIRNEVDPAH 459
            |||||:||||||.||||:|||||||||||.|||||||::|.|||||||||||||.|:|||.|||.
 Frog   392 LYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPAL 456

  Fly   460 ALLSDYIDNQNSCMRVGAILGLGIAYAGSNRSIVIDTLKTVFSFGSNNKSSASVEILGITALSLG 524
            ||||||:.:.::.||:|||.|||:|||||||..|:..|..|.     ..|.:|:|::|:|||:.|
 Frog   457 ALLSDYVLHNSNTMRIGAIFGLGLAYAGSNREDVLTLLLPVM-----GDSKSSMEVVGVTALACG 516

  Fly   525 LISVGSCNSEITEILLQTIMGLTKADLKDTYTRFLFLGLGLLYLGRQKSTEAVMMTLEVLEEPYR 589
            :|:|||||.::|..:|||||..::.:||||:.|:|.|||||.:||:.::.||::..|||:.||:|
 Frog   517 MIAVGSCNGDVTSTILQTIMEKSEQELKDTFARWLPLGLGLNHLGKGEAIEAILAALEVVPEPFR 581

  Fly   590 SMATTMVDICAYAGTGNVLKIQQLLHICSDHYETSSADDEKEKSKKDKGKDKEKEKEKEKEKERE 654
            |.|.|:||||||||:|||||:||||||||:||::...|||| |.||||             ||..
 Frog   582 SFANTLVDICAYAGSGNVLKVQQLLHICSEHYDSKEKDDEK-KDKKDK-------------KESA 632

  Fly   655 KDLSATQSIAVLGIALIAMGEDIGAEMAYRSFGNLLRYCEPAIRRAVPLALGLISASNPKLNIID 719
            .|:.:.|.:||||||||||||:||:|||.|:||:||||.||.:||||||||.|||.|||:|||:|
 Frog   633 ADMGSHQGVAVLGIALIAMGEEIGSEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILD 697

  Fly   720 TLSKFSHDSDAEVAHNAIFAMGLVGAGTNNARLASMLRQLAQYHSKDPSNLFMVRIAQSLTHLGK 784
            ||||||||:|.||::|:|||||:||:||||||||:|||||||||:|||:||||||:||.||||||
 Frog   698 TLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGK 762

  Fly   785 GTLSLSPYHSDRQLMNPMAVAGLMATLVSLLDVKNLILNRSHYLLYTLVPAMQARMLITFDEELN 849
            |||:|.|||||||||:.:|||||:..|||.|||:|::|.:|||:||.||.|||.|||:||||||.
 Frog   763 GTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIVLGKSHYVLYGLVAAMQPRMLVTFDEELR 827

  Fly   850 QLQVPVRVGIAIDVVGQAGKPKTITGFQTHTTPVLLAIGERAELATDEYLALTPVMEGFVILKKN 914
            .|.|.||||.|:|||||||||||||||||||||||||.||||||||:|||.:||::||||||:||
 Frog   828 PLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEYLPVTPILEGFVILRKN 892

  Fly   915 PNF 917
            ||:
 Frog   893 PNY 895

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn1	NP_649158.1	RPN1	61..919	CDD:227441	542/860 (63%)
psmd2	NP_001015819.1	RPN1	1..895	CDD:227441	563/911 (62%)