DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mtr3 and EXOSC5

DIOPT Version :9

Sequence 1:NP_649157.1 Gene:Mtr3 / 40173 FlyBaseID:FBgn0036916 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_064543.3 Gene:EXOSC5 / 56915 HGNCID:24662 Length:235 Species:Homo sapiens


Alignment Length:200 Identity:45/200 - (22%)
Similarity:77/200 - (38%) Gaps:40/200 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 VLTTVRGSAYMEYGNTKVLAIVAPPKELIRASARRMNMGVLNCYVNFAAFSTGDLDSVPERERHL 120
            :|:...|||....|:|.|||.|..|.| ::.|....|...|...:.    ....|..|.|:.|  
Human    37 LLSRPDGSASFLQGDTSVLAGVYGPAE-VKVSKEIFNKATLEVILR----PKIGLPGVAEKSR-- 94

  Fly   121 SSMLTKAMEPVVCRTEFLNFQLDIRVLILDDDGCLLSTAINCCGVALVECGISTYDLITASTACI 185
            ..::....|.||..|......:.:.:.::.|.|.||:..:|...:|||:.|:....|.......:
Human    95 ERLIRNTCEAVVLGTLHPRTSITVVLQVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACAL 159

  Fly   186 YRD-HVFLNPSAKVEELLWKHRNSSTDSTTSPSSAQEHGLIITASMDTFEQ------------IA 237
            ..| .:.|:|::|.|                    :|...::|.::|:.|:            ..
Human   160 DSDGTLVLDPTSKQE--------------------KEARAVLTFALDSVERKLLMSSTKGLYSDT 204

  Fly   238 QCQQC 242
            :.|||
Human   205 ELQQC 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Mtr3NP_649157.1 RNase_PH 47..274 CDD:295670 44/199 (22%)
EXOSC5NP_064543.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
ECX1 28..232 CDD:131120 44/199 (22%)
RNase_PH_RRP46 28..225 CDD:206777 44/199 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0689
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53663
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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