DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mtr3 and exosc6

DIOPT Version :9

Sequence 1:	NP_649157.1	Gene:	Mtr3 / 40173	FlyBaseID:	FBgn0036916	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_001017016.1	Gene:	exosc6 / 549770	XenbaseID:	XB-GENE-998313	Length:	270	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	72/249 - (28%)
Similarity:	117/249 - (46%)	Gaps:	32/249 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SEDFFESLDKPSREPTQLAPRNTFIRAGVLTTVRGSAYMEYGN--TKVLAIVAPPKELIRASARR 90
            ||:..::..:..|.|::  ||..|:|||:|:..:||||:|.|:  ||||..|..|:|......|.
Frog    23 SEEGGKAAGRRGRGPSE--PRPVFVRAGLLSQAKGSAYLEAGSGGTKVLCAVHGPRERGMGGERA 85

  Fly    91 MNMGVLNCYVNFAAFS-----TGDLDSVPERERHLSSMLTKAMEPVVCRTEFLNFQLDIRVLILD 150
            ...|.|.|.:.:|.||     :|...:.|. .|.....|.:::||.|....:...::.:.||:|:
Frog    86 ETRGRLLCDLRWAPFSRRGPWSGSCPAGPS-PRQAGLQLQESLEPAVRLDRYPRAEVIVWVLVLE 149

  Fly   151 DDGCLLSTAINCCGVALVECGISTYDLITASTAC-IYR---DHVFLNPSAKVEELLWKHRNSSTD 211
            |.|..|..|::|..:||.:.||..:||   :..| :.|   ..:.|:|....||       :.:.
Frog   150 DRGSALPAAVSCASLALADAGIEMFDL---ALGCGLSRGPGGELLLDPDDDEEE-------AGSG 204

  Fly   212 STTS----PSSAQEHGLIITASMD---TFEQIAQCQQ-CGYLSPATYVKLLDYT 257
            .|.|    |:..|..|||.:...:   :.|.:..|.: |..|.|..:..|:..|
Frog   205 GTMSLSLLPTLNQVSGLISSGEWEGESSEEAVRLCMEGCQRLYPVLHQCLVKAT 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mtr3	NP_649157.1	RNase_PH	47..274	CDD:295670	68/230 (30%)
exosc6	NP_001017016.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..42		5/20 (25%)
exosc6	NP_001017016.1	RNase_PH_MTR3	40..256	CDD:206776	67/226 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53663
OrthoDB	1	1.010	-	-		D1101132at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11953
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R763
SonicParanoid	1	1.000	-	-		X4850
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060