Protein Alignment Mtr3 and EXOSC4

DIOPT Version :9

• Sequence 1: NP_649157.1
• Gene: Mtr3 / 40173
• FlyBaseID: FBgn0036916
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_061910.1
• Gene: EXOSC4 / 54512
• HGNCID: 18189
• Length: 245
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 62/230 - (26%)
• Similarity: 99/230 - (43%)
• Gaps: 23/230 - (10%)

  Fly    53 RAGVLTTVRGSAYMEYGNTKVLAIVAPPKELIRASARRM-NMGVLNCYVNFAAFSTGDLDSVPER 116
            |.||.....||||:|.||||.||:|..|.|:..:.||.: :..::||..:.|.||||:....|..
Human    28 RMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVNCQYSSATFSTGERKRRPHG 92

  Fly   117 ERHLSSM---LTKAMEPVVCRTEFLNFQLDIRVLILDDDGCLLSTAINCCGVALVECGISTYDLI 178
            :|....|   |.:..|..:........|:||.|.:|..||...:..:|...:|:::.||...|.:
Human    93 DRKSCEMGLQLRQTFEAAILTQLHPRSQIDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFV 157

  Fly   179 TASTACIYRDHVFLNPSAKVEELLWKHRNSSTDSTTSPSSAQEHGLIITASMDTFEQIAQCQQCG 243
            .|.:|. :.|...|...:.|||           :...|..|       .|.:....|||..:...
Human   158 CACSAG-FVDGTALADLSHVEE-----------AAGGPQLA-------LALLPASGQIALLEMDA 203

  Fly   244 YLSPATYVKLLDYTLAINKSLRELVKGVLTKRVKE 278
            .|......::|:......:.:..|:..|:.:.|:|
Human   204 RLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVRE 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtr3	NP_649157.1	RNase_PH	47..274	CDD:295670	60/224 (27%)
EXOSC4	NP_061910.1	RNase_PH_RRP41	11..237	CDD:206775	60/227 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0689
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S936
OMA	1	1.010	-	-		QHG53663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001991
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770