Protein Alignment Mtr3 and EXOSC6

DIOPT Version :9

• Sequence 1: NP_649157.1
• Gene: Mtr3 / 40173
• FlyBaseID: FBgn0036916
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_478126.1
• Gene: EXOSC6 / 118460
• HGNCID: 19055
• Length: 272
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 57/181 - (31%)
• Similarity: 82/181 - (45%)
• Gaps: 33/181 - (18%)

  Fly    12 LDGASIEEEPYTTPQESEDFFESLDKPSREPTQLAPRNTFIRAGVLTTVRGSAYMEYGNTKVLAI 76
            |..|..||.|.|                |:||:|.|  .:.|||:|:..:||||:|.|.||||..
Human    19 LYAADEEEAPGT----------------RDPTRLRP--VYARAGLLSQAKGSAYLEAGGTKVLCA 65

  Fly    77 VAPPKEL-----------IRASARRMNMGVLNCYVNFAAFSTGDLDSVPE---RERHLSSMLTKA 127
            |:.|::.           ....|.....|.|.|....|.|: |.....|.   .||.|:..|.:|
Human    66 VSGPRQAEGGERGGGPAGAGGEAPAALRGRLLCDFRRAPFA-GRRRRAPPGGCEERELALALQEA 129

  Fly   128 MEPVVCRTEFLNFQLDIRVLILDDDGCLLSTAINCCGVALVECGISTYDLI 178
            :||.|....:...||::..|:|:|.|..|:.|:....:||.:.|:..|||:
Human   130 LEPAVRLGRYPRAQLEVSALLLEDGGSALAAALTAAALALADAGVEMYDLV 180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtr3	NP_649157.1	RNase_PH	47..274	CDD:295670	47/146 (32%)
EXOSC6	NP_478126.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		9/32 (28%)
		RNase_PH_MTR3	36..260	CDD:206776	48/148 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152420
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0689
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53663
OrthoDB	1	1.010	-	-		D1101132at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102545
Panther	1	1.100	-	-	LDO	PTHR11953
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R763
SonicParanoid	1	1.000	-	-		X4850
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.750