Protein Alignment Su(Tpl) and LOC565819

DIOPT Version :9

• Sequence 1: NP_001163477.1
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: XP_694180.3
• Gene: LOC565819 / 565819
• -ID: -
• Length: 593
• Species: Danio rerio
• Alignment Length: 948
• Identity: 204/948 - (21%)
• Similarity: 324/948 - (34%)
• Gaps: 394/948 - (41%)

  Fly    22 MSQSHRY---------TDDSKEYIIVKLTDSAFRAIEEYQRDDNAKRLQPGQRAKIQFVGNTGVI 77
            :.|.|||         :..:|....|||||:|.|.:|.||   |.|...|.|.| |.|.||.|.|
Zfish     4 LRQEHRYGLSCGKINKSIPNKTIFHVKLTDTAIRTLEAYQ---NLKGSLPNQPA-ICFKGNQGYI 64

  Fly    78 QFPRPATDANGIPNANGNGSDATGAGGGGGRKFGFTINN-----MEGTLECVQQ------QQRSL 131
            :.|           |:.:..||.       |.|.|.:::     .:.:.:||.|      :.|..
Zfish    65 KIP-----------ASSDSPDAF-------RVFSFYLSSDSKDKPQASFDCVHQFVSGDGRDRLE 111

  Fly   132 GVLGAVTLRMRIHANEDVYDSTRTKMAIAEETEKSKCIREIKPNQSDIGRKVKKPPSAIQSSAST 196
            | .|::..::.:.|.:|.|..||.:|:..|:...|:...||||..:...:.||     |:...|.
Zfish   112 G-QGSIQDKITVCATDDSYQMTRERMSQVEKDIWSRSAIEIKPGSTRPSKCVK-----IKKKQSL 170

  Fly   197 ASAFSSNSSNSGLTTTAFHHHSNSNNSGNNNNRSSSSSNSFNSNNHSRKLGSSPFNGLGVGSSSS 261
            :::|.|                                    :|.||
Zfish   171 SASFDS------------------------------------TNKHS------------------ 181

  Fly   262 SSAFASRSPNPSTLGAIGTVNGSGVVGGRYGGGAASSLASTFANGISQGYHNLSGSSPRDSMTAG 326
                                                                             
Zfish   182 ----------------------------------------------------------------- 181

  Fly   327 TSSATASSVISSRNKMPSGGLTSSNSNSSSSSRSANSKSSGGNKMSDVSRRNIRERLIHLLALKA 391
                            ||                  :|.:||..:  |:.|.:|||:||:||||.
Zfish   182 ----------------PS------------------NKRNGGPSL--VTHRPLRERVIHILALKP 210

  Fly   392 FKKPELFARLKNEGIRDRERNQITNILMDISTMS--HNTYNLRRQMWNDVDENWPFFSEQEVQQL 454
            :.||||...|:.|....:::..::.:|.:::.::  .:::.|:...:..|.::||.:.|:|.|.:
Zfish   211 YSKPELLLWLEREKASPKDKADLSPVLDEVAKLNPKEHSFTLKDDFYRHVRKDWPGYVEEERQLI 275

  Fly   455 KR---RKPQNLTPPMSSDAGSS--TSGQSPTSTHTGSPPPPSSNGGPGGVGSGAGGTSMKR-TSL 513
            :|   ||.|    |:||.:.||  .|.||..|.|..|...||..       |.....|||| ...
Zfish   276 QRVLARKLQ----PLSSSSSSSQLKSFQSSHSFHKTSGDSPSQL-------SPVKTPSMKRPVPS 329

  Fly   514 EYDETMFSTVQPKKQRI--SHYKKDTPPSGTSYSSAGVSMSLGSSGSSSRSRYTPPQRQPGPLDD 576
            ::.|:.    .|||||:  .:....:|.:|...||.|.|.|  |.|::|..|        ||
Zfish   330 DHPESQ----TPKKQRLLEQNIPLQSPSNGHLSSSVGRSSS--SHGNTSLQR--------GP--- 377

  Fly   577 HSTTDLSYNVLDNIVEFMSSTAAATQQSMEQQQHPRSNSSNNRRGSSSLAGTSNGGNNKDKRNST 641
              .||..|                       |:|                 ..|.||:..|
Zfish   378 --NTDEFY-----------------------QRH-----------------KLNEGNSLPK---- 396

  Fly   642 GSNSSSSSGYETQQDRQRSTTPMSSNRSSASSSTTPPKLAASFVPAATSGSASGTSKQRMPPQQS 706
                       |:|....:::|....|       |.|::.              |.:|..
Zfish   397 -----------TEQPEPAASSPHKHPR-------TEPEIC--------------TDQQLA----- 424

  Fly   707 DYNSYNSNNAQHVASNSKKRMGSVGPSGGSNGQRQRSASGSNSGYQQVPPPSSNSRSSIQQQNQH 771
                    |.||....|||             .:::........:.:..|...:::.:|   |.|
Zfish   425 --------NGQHKKKKSKK-------------HKEKERERLKPEWVETSPDLKHNQENI---NDH 465

  Fly   772 QKQQVQQKQAPSQQQQQQQQQYHQQAKHPSPSQQLAAAAHAYAHATADTDSSATPRYDFSQYVPI 836
            ::......:|                   ||.|                    .|.| ..:|..|
Zfish   466 ERPNTPVTRA-------------------SPDQ--------------------LPDY-LLKYNTI 490

  Fly   837 QTLEVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYGDYDHIKRQIVCEY 901
            ...|.|:|||.:|.::|||||.|..|:..|...|..|..::::   ...|..:|..::.||:.:|
Zfish   491 TDSEQRQRYKEDFCAEYDEYRDLHERIGKVTEIFVQLGSKIKT---LSPGTQEYKVMEDQIMEKY 552

  Fly   902 ERINNDRTIG--EDKERFDYLHAKLAHIKQLVMDYDKT 937
            ::... :..|  |:|:|.:|||.||:|||.|::|||:|
Zfish   553 KKYKK-KFPGYREEKKRCEYLHQKLSHIKGLILDYDQT 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_001163477.1	ELL	16..460	CDD:287376	93/462 (20%)
		Occludin_ELL	836..935	CDD:284669	36/100 (36%)
LOC565819	XP_694180.3	ELL	6..281	CDD:287376	91/457 (20%)
		Occludin_ELL	490..587	CDD:284669	36/100 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579778
Domainoid	1	1.000	131	1.000	Domainoid score	I5113
eggNOG	1	0.900	-	-		E1_KOG4796
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3594
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D170004at33208
OrthoFinder	1	1.000	-	-		FOG0002166
OrthoInspector	1	1.000	-	-		otm24840
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23288
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1874
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.950