Protein Alignment Su(Tpl) and ell

DIOPT Version :9

• Sequence 1: NP_001163477.1
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: NP_956001.1
• Gene: ell / 325221
• ZFINID: ZDB-GENE-030131-3946
• Length: 633
• Species: Danio rerio
• Alignment Length: 943
• Identity: 205/943 - (21%)
• Similarity: 329/943 - (34%)
• Gaps: 352/943 - (37%)

  Fly    20 YGMSQSHRYTDDSKEYII-VKLTDSAFRAIEEYQRDDNAKRLQPGQRAK--IQFVGNTGVIQFPR 81
            ||:| ..|.::.||..:. |||||||.||.|:||.:       .|..||  |.|.|:.|.|..|:
Zfish    10 YGLS-CGRVSNGSKISVYHVKLTDSALRAFEDYQSN-------KGLTAKPLIGFTGSQGKISIPQ 66

  Fly    82 PATDANGIPNANGNGSDATGAGGGGGRKFGFTINNM-----EGTLECVQQQQRS-----LGVLGA 136
            ...     ||..              |.|.|.::|:     :|:.:|:||...|     |..||.
Zfish    67 SEN-----PNEL--------------RTFTFYLSNVGKDNPQGSFDCIQQYITSEGSIQLDCLGG 112

  Fly   137 VTLRMRIHANEDVYDSTRTKMAIAEETEKSKCIREIKPNQSDIGRKVKKPPSAIQSSASTASAFS 201
            :..::.:.|.:|.|...|..||..||..:|:....|||....:|::|:
Zfish   113 IQDKITVCATDDSYQKARQSMAQVEEETRSRGAIVIKPGGRYVGKRVQ----------------- 160

  Fly   202 SNSSNSGLTTTAFHHHSNSNNSGNNNNRSSSSSNSFNSNNHSRKLGSSPFNGLGVGSSSSSSAFA 266
                                                     .||    |..|:      |..|.:
Zfish   161 -----------------------------------------IRK----PITGV------SDVAPS 174

  Fly   267 SRSPNPSTLGAIGTVNGSGVVGGRYGGGAASSLASTFANGISQGYHNLSGSSPRDSMTAGTSSAT 331
            .|:..|
Zfish   175 RRTSRP----------------------------------------------------------- 180

  Fly   332 ASSVISSRNKMPSGGLTSSNSNSSSSSRSANSKSSGGNKMSDVSRRNIRERLIHLLALKAFKKPE 396
              .:|||                     ||..||         ..|.:||||:||||||.::|||
Zfish   181 --VIISS---------------------SAQKKS---------PPRPLRERLVHLLALKPYRKPE 213

  Fly   397 LFARLKNEGIRDRERNQITNILMDISTMS--HNTYNLRRQMWNDVDENWPFFSEQEVQQLKRRKP 459
            |..||..:|:..:::..:.::|..::.::  .||:.|:..::.:|.::||.::|.:.|.|||...
Zfish   214 LLVRLTKDGLSFQDKETLDSLLQQVANLNSKDNTFTLKDCLFKEVQKDWPGYTEVDQQILKRILV 278

  Fly   460 QNLTPPMSSDAGSSTSGQSPTSTH---TGSPPPPSSNGGPGGVGSGAGGTSMKRTSLEYDETMFS 521
            :.|..|.|:   :..|.:||.|.|   ..|.|...:...|           .||.:.::.:.:.:
Zfish   279 RKLCKPQSN---APVSVESPVSPHKEPASSSPSQLNTHNP-----------QKRPAADFIDPLAN 329

  Fly   522 TVQPKKQRISHY--KKDTPPSGTSYSSAGVSMSLGSSGSSSRSRYTPPQRQPGPLDDHSTTDLSY 584
                ||.||||.  |.....:|...||.|...|...:..:|.|...||...|.|.|
Zfish   330 ----KKPRISHLVSKSTGLINGKLSSSNGKDTSSSQATETSSSSQFPPLEIPRPFD--------- 381

  Fly   585 NVLDNIVEFMSSTAAATQQSMEQQQHPRSNSSNNRRGSSSLAGTSNGGNNKDKRNSTGSNSSSSS 649
                                      |.|:.||:          |||.:.:.:..:.....|...
Zfish   382 --------------------------PLSDVSND----------SNGRDCEGQEAAVAERLSQPP 410

  Fly   650 GY----ETQQDRQRSTTPMSSNRSSASSSTTPPKLAASFVPAATSGSASGTSKQRMPPQQSDYNS 710
            .:    .||::||.|.:|..|:..|:.:.||.|.|             .|.||::
Zfish   411 SFAPRSATQEERQTSMSPPHSSLDSSLTQTTQPSL-------------HGKSKKK---------- 452

  Fly   711 YNSNNAQHVASNSKKRMGSVGPSGGSNGQRQRSASGSNSGYQQVPPPSSNSRSSIQQQNQHQKQQ 775
                        |||..                                      .:.....|.:
Zfish   453 ------------SKKHK--------------------------------------DKDKSKDKDR 467

  Fly   776 VQQKQAPSQQQQQQQQQYHQQAKHPSPSQQLAAAAHAYAHATA-DTDSSATPRYDFSQYVPIQTL 839
            .:::.|..:::..:::...|:......:...:...:...:::: ...||.|..| ..:|..|.:.
Zfish   468 DRERDAKKERRVDEERGLDQRKPCDVTTSDKSTGLNGTCNSSSIPASSSETADY-LIKYTVISSP 531

  Fly   840 EVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYGDYDHIKRQIVCEYERI 904
            |.|:.||.:|.|:|.|||.|..|:|.:..:|..|...|   ::...|...|..|..||:.||.:|
Zfish   532 EQRQTYKNDFNSEYSEYRGLHARIESITRQFTILDSEL---KQLQQGTDKYKTIHNQILEEYRKI 593

  Fly   905 -NNDRTIGEDKERFDYLHAKLAHIKQLVMDYDK 936
             ..:....::|.|.:|||.||||||:|:.:||:
Zfish   594 KKTNPNYSQEKNRCEYLHNKLAHIKKLIAEYDQ 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_001163477.1	ELL	16..460	CDD:287376	100/454 (22%)
		Occludin_ELL	836..935	CDD:284669	37/99 (37%)
ell	NP_956001.1	ELL	6..279	CDD:287376	100/454 (22%)
		Occludin_ELL	528..625	CDD:284669	37/99 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579772
Domainoid	1	1.000	131	1.000	Domainoid score	I5113
eggNOG	1	0.900	-	-		E1_KOG4796
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3594
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D170004at33208
OrthoFinder	1	1.000	-	-		FOG0002166
OrthoInspector	1	1.000	-	-		otm24840
orthoMCL	1	0.900	-	-		OOG6_100830
Panther	1	1.100	-	-	O	PTHR23288
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1874
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.850