DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(Tpl) and Ell3

DIOPT Version :9

Sequence 1:	NP_001163477.1	Gene:	Su(Tpl) / 40171	FlyBaseID:	FBgn0014037	Length:	1059	Species:	Drosophila melanogaster
Sequence 2:	NP_666085.2	Gene:	Ell3 / 269344	MGIID:	2673679	Length:	395	Species:	Mus musculus

Alignment Length:	295	Identity:	70/295 - (23%)
Similarity:	120/295 - (40%)	Gaps:	47/295 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   671 ASSSTTP-PKLAASFVPAATSGSASGTS--------KQRMPPQQSDYNSYNSNNAQHVASNSKKR 726
            |:..|.| |.||...:...|..|.|...        .|..|.:.||  ...|::.|.:..:|.:.
Mouse   114 AAMDTIPAPLLAQEHLTEGTRESESWQDTGDEPEGHPQLAPDEVSD--PLASHHEQSLPGSSSEP 176

  Fly   727 MGSVGPSGGSNGQRQRSASGSNSGYQQVPPPSSNSRSSIQQQNQHQKQQVQQK------------ 779
            |...       ..|..:...|....|.:..|:|..|...::......::.::|
Mouse   177 MAQW-------EMRNHTYLPSREPDQSLLSPASQKRLDKKRSAPITTEEPEEKRLRALPLASSPL 234

  Fly   780 QAPSQQQQQQQQQYHQQAKHPSP-------SQQLAAAAHAYAHATADTDSSATPRYDFSQYVPIQ 837
            |..:.|..|:.:.:.|.......       .|.|:|.:     |:........|.| ..||..|.
Mouse   235 QGLANQDSQEGEDWGQDEDEEGDEDGDSRLEQSLSAPS-----ASESPSPEEVPDY-LLQYRAIH 293

  Fly   838 TLEVRRRYKTEFESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYGDYDHIKRQIVCEYE 902
            :.|.::.|:.:||:||.|||.|..||.....||.:|...:   :|...|..::..::.:||.||:
Mouse   294 STEQQQAYEQDFETDYAEYRILHARVGAASQRFTELGAEI---KRLQRGTPEHKVLEDKIVQEYK 355

  Fly   903 RINND-RTIGEDKERFDYLHAKLAHIKQLVMDYDK 936
            :.... .:..|:|.|.:|||.||:|||.|::::::
Mouse   356 KFRKRYPSYREEKHRCEYLHQKLSHIKGLILEFEE 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_001163477.1	ELL	16..460	CDD:287376
Su(Tpl)	NP_001163477.1	Occludin_ELL	836..935	CDD:284669	34/99 (34%)
Ell3	NP_666085.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..177		10/49 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	189..281		14/96 (15%)
		Occludin_ELL	292..389	CDD:284669	34/99 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836306
Domainoid	1	1.000	79	1.000	Domainoid score	I8640
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43800
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23288
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.030