Protein Alignment Su(Tpl) and ell3

DIOPT Version :10

• Sequence 1: NP_649155.3
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: XP_002932307.1
• Gene: ell3 / 100492932
• XenbaseID: XB-GENE-999062
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 933
• Identity: 174/933 - (18%)
• Similarity: 303/933 - (32%)
• Gaps: 391/933 - (41%)

  Fly    38 VKLTDSAFRAIEEYQRDDNA--KRLQPGQRAKIQFVGNTGVIQFPRPATDANGIPNANGNGSDAT 100
            :||||||.|.:.::||...:  ..|||    .|.|.||.|.|:.|.|:      |.....
 Frog    29 LKLTDSALRCLRDFQRGQGSGPSSLQP----VITFQGNQGYIKIPSPS------PGCEDR----- 78

  Fly   101 GAGGGGGRKFGFTI-----NNMEGTLECVQQ-----QQRSLGVLGAVTLRMRIHANEDVYDSTRT 155
                  .|.|.|.:     :..:.:.||::|     .::.|..:|::..::.:.|.::.|..||.
 Frog    79 ------VRIFAFYLSRESKDKPQSSFECIRQGTSWSGEKQLSCIGSIQDKITVCATDESYQLTRD 137

  Fly   156 KMAIAEETEKSKCIREIKPNQSDIGRKVKKPPSAIQSSASTASAFSSNSSNSGLTTTAFHHHSNS 220
            :::..|:...|:...||||..|...:..|.|
 Frog   138 RVSQVEKETWSRTAIEIKPEASHRSKYAKIP---------------------------------- 168

  Fly   221 NNSGNNNNRSSSSSNSFNSNNHSRKLGSSPFNGLGVGSSSSSSAFASRSPNPSTLGAIGTVNGSG 285
                        :.|:..:|....:                    .||.|:.....|....|..|
 Frog   169 ------------AKNTVEANKEESQ--------------------CSRRPHVFLTPAAKKCNRVG 201

  Fly   286 VVGGRYGGGAASSLASTFANGISQGYHNLSGSSPRDSMTAGTSSATASSVISSRNKMPSGGLTSS 350
                                                                             
 Frog   202 ----------------------------------------------------------------- 201

  Fly   351 NSNSSSSSRSANSKSSGGNKMSDVSRRNIRERLIHLLALKAFKKPELFARLKNEGIRDRERNQIT 415
                                   |..|.::|.::||||||.:||.::.|||:..|...||:.::.
 Frog   202 -----------------------VENRPLQEWVVHLLALKPYKKQDIIARLEKAGENLREQKELL 243

  Fly   416 NILMDISTMS--HNTYNLRRQMWNDVDENWPFFSEQEVQQLK---RRKPQNLTPPMSSDAGSSTS 475
            ..|..:..::  ..:|:|:.:.:..|..:|..:|.:|.|.::   .||..|:          |.|
 Frog   244 ATLDLVGQLNPKDGSYSLKEEFYIQVQTDWVGYSPEERQHIESTLSRKHLNI----------SAS 298

  Fly   476 GQSPTSTHTGSPPPPSSNGGPGGVGSGAGGTSMKRTSLEYDETMFSTVQPKKQRISHYKKDTPPS 540
            ...|.|    .|.||                                     ||..|    .|||
 Frog   299 RNIPAS----MPAPP-------------------------------------QRTQH----GPPS 318

  Fly   541 GTSYSSAGVSMSLGSSGSSSRSRYTPPQRQPGPLDDHSTTDLSYNVLDNIVEFMSSTAAATQQSM 605
              |||||
 Frog   319 --SYSSA---------------------------------------------------------- 323

  Fly   606 EQQQHPRSNSSNNRRGSSSLAGTSNGGNNKDKRNSTGSNSSSSSGYETQQDRQRSTTPMSSNRSS 670
                  |...|.::|..:  |.|::.|:.|..:.|           ..::.::.||:|...|  |
 Frog   324 ------RGQHSESKRPHA--AETADNGSCKKIKTS-----------HLEKHQRHSTSPPVLN--S 367

  Fly   671 ASSSTTPPKLAASFVPAATSGSASGTSKQRMPPQQSDYNSYNSNNAQHVASNSKKRMGSVGPSGG 735
            .||..|.|:..||..|              :|...|.|:.:......:..|..|
 Frog   368 NSSHQTSPETCASLCP--------------VPENHSVYSLHTHKKQSYHRSVPK----------- 407

  Fly   736 SNGQRQRSASGSNSGYQQVPPPSSNS-----RSSIQQQNQHQKQ----QVQQKQAPSQQQQQQQQ 791
                    :....|..:::|..:.||     |.:..|.:|.|||    :..:|:..|.:.::::.
 Frog   408 --------SQNRESHKEKIPREAQNSEKAKPRGATSQCSQAQKQSEWNKAGKKEQDSSEDEEEED 464

  Fly   792 QYHQQAKH-------PSPSQQLAAAAHAYAHATADTDSSATPRYDFSQYVPIQTLEVRRRYKTEF 849
            .:.::|..       |....|.|.:|         :.|:..|.| ..:|.||.:.:.|:.|:.:|
 Frog   465 DWEEEALQLERCLCSPEEKPQRAESA---------SPSAEIPDY-CKKYRPITSADQRQVYEKDF 519

  Fly   850 ESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYGDYDHIKRQIVCEYERINNDRT-IGED 913
            .:||.||.:|..::..|::||..|..::   ::...|..::..:.::|:.||::...... ..|:
 Frog   520 TADYTEYLELHAKIGKVQDRFVRLGAKM---KKLQQGTVEHKMVGKKILAEYKKFKMTYPGYREE 581

  Fly   914 KERFDYLHAKLAHIKQLVMDYDK 936
            |.:.:|||.||:|||||:::|:|
 Frog   582 KAKCEYLHHKLSHIKQLILEYEK 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_649155.3	ELL	16..462	CDD:463068	77/440 (18%)
		Occludin_ELL	833..936	CDD:462140	32/103 (31%)
ell3	XP_002932307.1	ELL	20..291	CDD:463068	75/436 (17%)
		Occludin_ELL	503..604	CDD:462140	32/103 (31%)