Protein Alignment Su(Tpl) and ell2

DIOPT Version :10

• Sequence 1: NP_649155.3
• Gene: Su(Tpl) / 40171
• FlyBaseID: FBgn0014037
• Length: 1059
• Species: Drosophila melanogaster
• Sequence 2: XP_002933477.1
• Gene: ell2 / 100038075
• XenbaseID: XB-GENE-481670
• Length: 630
• Species: Xenopus tropicalis
• Alignment Length: 940
• Identity: 204/940 - (21%)
• Similarity: 326/940 - (34%)
• Gaps: 346/940 - (36%)

  Fly    18 GNYGMSQSHRYTDDSKEYIIVKLTDSAFRAIEEYQRDDNAKRLQPGQRAKIQFVGNTGVIQFPRP 82
            |.||:| ..|.|.|....:.||||::||||:|.||...|:...:|    .|||.|..|.|:.|:|
 Frog     9 GRYGLS-CGRGTQDQVTVLHVKLTETAFRALESYQNTKNSLTSRP----SIQFQGLQGCIKIPKP 68

  Fly    83 ATDANGIPNANGNGSDATGAGGGGGRKFGFTINNM-----EGTLECVQQQQRSLGV-----LGAV 137
                           |..    |....|.|.::|:     :|:.:|:||...|.|:     ||.:
 Frog    69 ---------------DCL----GDVHNFNFYLSNVGKDNPQGSFDCIQQTVSSSGLSKLNCLGCI 114

  Fly   138 TLRMRIHANEDVYDSTRTKMAIAEETEKSKCIREIKPNQSDIGRKV--KKPPSAIQSSASTASAF 200
            ..::.:.|..|.|..||.:|..|||..:|:..:.|||....:|::|  :||.:.|..:|.
 Frog   115 QDKITVCATNDSYQLTRDRMTQAEEETRSRSTKVIKPGGPFVGKRVQIRKPATNILDTAP----- 174

  Fly   201 SSNSSNSGLTTTAFHHHSNSNNSGNNNNRSSSSSNSFNSNNHSRKLGSSPFNGLGVGSSSSSSAF 265
                                                      .|| .|:|.|
 Frog   175 ------------------------------------------ERK-RSTPIN------------- 183

  Fly   266 ASRSPNPSTLGAIGTVNGSGVVGGRYGGGAASSLASTFANGISQGYHNLSGSSPRDSMTAGTSSA 330
                                                                             
 Frog   184 ----------------------------------------------------------------- 183

  Fly   331 TASSVISSRNKMPSGGLTSSNSNSSSSSRSANSKSSGGNKMSDVSRRNIRERLIHLLALKAFKKP 395
                        |:..:..||.:|.                  :::|..|||:|||||||.:|||
 Frog   184 ------------PASTIRKSNQSSV------------------IAQRPYRERVIHLLALKPYKKP 218

  Fly   396 ELFARLKNEGIRDRERNQITNILMDISTMS--HNTYNLRRQMWNDVDENWPFFSEQEVQQLKRRK 458
            |:.|||..:|:..:::|.:..||..::.::  .|:|.|:..::.::..:||.:.|.:    |...
 Frog   219 EILARLHKDGVNQKDKNSLGVILQQVANLNPKDNSYTLKDFVYKEIQRDWPGYLEGD----KHLL 279

  Fly   459 PQNLTPPMSSDAGSSTSGQSPTSTHTGSPPPPSSNGGPGGVGSGAGGTSMKRTSLEYDETMFSTV 523
            .|.|:..::....::||...|.|      ||.:::..|          |.||   ..|......:
 Frog   280 DQVLSRKLNQSQSNTTSTSQPDS------PPMATSSSP----------SQKR---PLDTEFIDPL 325

  Fly   524 QPKKQRISHYKKDTPPSGTSYSSAGVSMSLGSSGSSSRSRYTPPQRQPGPLDDHSTTDLSYNVLD 588
            ..||.||||......|          :|:...|.::.:|.:.||
 Frog   326 MNKKPRISHLTNRVQP----------TMNGHLSSANEKSAHAPP--------------------- 359

  Fly   589 NIVEFMSSTAAATQQSMEQQQHPRSNSSNNRRGSSSLAGTSNGGNNKDKRNSTGSNSSSSSGYET 653
                  .|.|..:...:...:.|.||..|....|:| ..|..|...:|.  ...|.|.:|..||.
 Frog   360 ------PSAATPSLLPLPTARLPVSNPQNINSNSNS-PSTPEGRGTQDL--PVDSFSQNSGTYED 415

  Fly   654 QQDRQRSTTPMSSN-----RSSASSSTTPPKLAASFVPAATSGSASGTSKQRMPPQQSDYNSYNS 713
            ||::..|.|.:.::     :.|.|.||..   .:|.:...|..:.....|:|   ::.|..:...
 Frog   416 QQEKYTSRTTLENSVPTQIKLSVSESTDD---KSSTLHKKTKKAKKHKDKER---KRRDSETAEE 474

  Fly   714 NNAQHVASNSKKRMGSVGPSGGSNGQRQRSASGSNSGYQQVPPPSSNSRSSIQQQNQHQKQQVQQ 778
            ..|.|:..:...:|            .|.|.|....|.:..
 Frog   475 TKAVHLKKDQIVKM------------EQSSCSERKKGLKDT------------------------ 503

  Fly   779 KQAPSQQQQQQQQQYHQQAKHPSPSQQLAAAAHAYAHATADTDSSATPRYDFS-QYVPIQTLEVR 842
                                                 .||...||.|...|:. :|..|.:.|.|
 Frog   504 -------------------------------------CTASDPSSTTELPDYMVKYTVIVSSEQR 531

  Fly   843 RRYKTEFESDYDEYRKLLTRVEDVRNRFQDLSERLESARRCDNGYGDYDHIKRQIVCEYERI-NN 906
            :.||.:|.|:|||||.|..|||:|..:|..|..:.:|   ...|..:|..:..:::.||.:: ..
 Frog   532 QSYKDDFNSEYDEYRSLHARVENVTRKFMQLDTQRKS---LSPGSKEYKTVHEEVLQEYRKMKET 593

  Fly   907 DRTIGEDKERFDYLHAKLAHIKQLVMDYDK 936
            .....|:|.|.:|||.||||||:|:.::|:
 Frog   594 SPNYYEEKYRCEYLHNKLAHIKRLIGEFDQ 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(Tpl)	NP_649155.3	ELL	16..462	CDD:463068	99/457 (22%)
		Occludin_ELL	833..936	CDD:462140	38/103 (37%)
ell2	XP_002933477.1	ELL	7..287	CDD:463068	100/461 (22%)
		BDP1	292..>545	CDD:227448	75/390 (19%)
		Occludin_ELL	522..623	CDD:462140	38/103 (37%)