Protein Alignment Mi-2 and ASG3

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_973689.2
• Gene: ASG3 / 819106
• AraportID: AT2G44980
• Length: 877
• Species: Arabidopsis thaliana
• Alignment Length: 908
• Identity: 291/908 - (32%)
• Similarity: 418/908 - (46%)
• Gaps: 203/908 - (22%)

  Fly   705 PPEKPTTDL----------------KKKYEDQPAFLE--GTGMQLHPYQIEGINWLRYSWGQGID 751
            ||:.|:|.:                :.|:.:.|....  |....|.|:|:||::||...:..|::
plant     7 PPKVPSTTMEYERRLEAAAEIILEKEAKFSNTPPDCSEFGVTATLKPHQVEGVSWLIQKYLLGVN 71

  Fly   752 TIL-ADEMGLGKTIQTVTFL-YSLYKEGHCRGPFLVAVPLSTLVNWEREFELWAPDFYCITYIGD 814
            .:| .|:||||||:|.::|| |..:::| ..|||||..|||....|..|...:.|:...:.|:||
plant    72 VVLELDQMGLGKTLQAISFLSYLKFRQG-LPGPFLVLCPLSVTDGWVSEINRFTPNLEVLRYVGD 135

  Fly   815 KDSRAVIRENELSFEEGAIRGSKVSRLRTTQYKFNVLLTSYELISMDAACLGSIDWAVLVVDEAH 879
            |..|..:|::.....:.:.:|..:        .|:||||:|::..:|...|..|.|...::|||.
plant   136 KYCRLDMRKSMYDHVKKSSKGHFL--------PFDVLLTTYDIALVDQDFLSQIPWQYAIIDEAQ 192

  Fly   880 RLKSNQSKFFRI-LNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDLQAFQGEF------ 937
            |||:..|..:.: |..:.|..:||:||||:||||.||:.|::|.....|..|..|...|
plant   193 RLKNPNSVLYNVLLEQFLIPRRLLITGTPIQNNLTELWALMHFCMPLVFGTLDQFLSAFKETGDG 257

  Fly   938 ---ADVSKE-EQVKRLHEMLGPHMLRRLKTDVLKN----MPSKSEFIVRVELSAMQKKFYKFILT 994
               .|||.: |..|.|..:||..||||.|:.::::    :|..:|..|.|.|.::|||.|..||.
plant   258 LSGLDVSNDKETYKSLKFILGAFMLRRTKSLLIESGNLVLPPLTELTVMVPLVSLQKKIYTSILR 322

  Fly   995 KNYEALNSKSGGGS--CSLINIMMDLKKCCNHPYLFPSAAEEATTAAGGLYEINSLTKAAGKLVL 1057
            |....|...|.|||  .||.||::.|:|.|:||||||....|.      ..|...|.:|:|||::
plant   323 KELPGLLELSSGGSNHTSLQNIVIQLRKACSHPYLFPGIEPEP------FEEGEHLVQASGKLLV 381

  Fly  1058 LSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQEAIDRFNA----- 1117
            |.::||:|....||||:|||||..||||:||:|..:|.|||:||.:....|..||..|:|
plant   382 LDQLLKRLHDSGHRVLLFSQMTSTLDILQDFMELRRYSYERLDGSVRAEERFAAIKNFSAKTERG 446

  Fly  1118 -----PGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRF 1177
                 .|:..|||::||||||:|:||..|||||.|:.||||..|.||..|||||||.:.|:....
plant   447 LDSEVDGSNAFVFMISTRAGGVGLNLVAADTVIFYEQDWNPQVDKQALQRAHRIGQISHVLSINL 511

  Fly  1178 VTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELD---------DILRFGTEDLFKED 1233
            ||.:||||.:.:.|:||:.|:|.||       |.|..::|.|         .:.||..|::..|:
plant   512 VTEHSVEEVILRRAERKLQLSHNVV-------GDNMEEKEEDGGDLRSLVFGLQRFDPEEIHNEE 569

  Fly  1234 -------------------------DKEEAIHYDDKAVAELLDRTNRGIEEKESWANEYLS---S 1270
                                     ||||. .::..:...||..|:....:.|.....|||   .
plant   570 SDNLKMVEISSLAEKVVAIRQNVEPDKEER-RFEINSSDTLLGNTSSASLDSELDEASYLSWVEK 633

  Fly  1271 FKVASYATKEEE----------EEEET---EIIKQDAENSDPAYWVKLLRHHYEQHQ-------E 1315
            .|.|:.::|:|:          .||..   |..::.||....|.|.   .|.|:...       :
plant   634 LKEAARSSKDEKIIELGNRKNLSEERNLRIEAARKKAEEKKLATWG---AHGYQSLSVEEPILPD 695

  Fly  1316 DVGRSLGKGKRVRKQVNYTDGGVVAADTTR----------DDS-NWQDNG-------------SE 1356
            ||..|...|     .||:..|......|..          ||| ||...|             :.
plant   696 DVDSSSDAG-----SVNFVFGDCTNPSTVSHEPAIIFSCVDDSGNWGRGGMFDALSKLSNTVPTA 755

  Fly  1357 YN--SEYSAGSDEDGGD------DDFDDQNGAERKA-------------KRRLERRDDRPLPPL- 1399
            |:  ||:   .|...||      ||.|||...:...             .||...|....:|.|
plant   756 YHRASEF---KDLHLGDLHLIKIDDNDDQQNTQASKPLWVAVAVTQSYNSRRKVPRSSISIPDLE 817

  Fly  1400 --LARVGGNIEVLGFNARQRKSFLNAIMRYGMPPQDAFN-SQWLVRDLRGKSERNFKAYVSLF 1459
              ||:.       .|:|.|:.:.|: :.|.|.  ||..: |||..      .||..:.|.|:|
plant   818 SCLAKA-------SFSASQKSASLH-MPRIGY--QDGSDRSQWYT------VERLLRKYSSIF 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357
		TNG2	<282..422	CDD:227367
		PHD1_CHD_II	380..422	CDD:277006
		PHD2_CHD_II	440..482	CDD:277007
		CD1_tandem_CHD3-4_like	487..557	CDD:349314
		CD2_tandem_CHD3-4_like	610..664	CDD:349309
		PLN03142	720..>1234	CDD:215601	214/578 (37%)
		DUF1087	<1292..1334	CDD:461922	12/48 (25%)
		CHDII_SANT-like	1380..1517	CDD:461920	23/97 (24%)
		CHDCT2	1757..1902	CDD:462358
ASG3	NP_973689.2	HepA	<46..537	CDD:440319	205/512 (40%)
		Macro_Poa1p-like_SNF2	705..864	CDD:394880	43/177 (24%)