Protein Alignment Mi-2 and SYD

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_001325348.1
• Gene: SYD / 817375
• AraportID: AT2G28290
• Length: 3575
• Species: Arabidopsis thaliana
• Alignment Length: 2091
• Identity: 509/2091 - (24%)
• Similarity: 791/2091 - (37%)
• Gaps: 540/2091 - (25%)

  Fly   197 GGAAGSGGSAGQARSVTGDEPEEPRSSRSSRNEKPDDIYEEAVEEEEEEEEEEKKPRRKRSGRGK 261
            |...|...||.|    |..:....:|:||...|.|.::...:...:.....|....|
plant   125 GRQLGGSNSASQ----TFYQGSGTQSNRSFDRESPSNLDSTSGISQPHNRSETMNQR-------- 177

  Fly   262 KGRRPSGKVPTLKIKLLGKRKRDSS----DEEQDASGA--SERDSDLEFE-RMLQKSDDSADEKE 319
                        .:|..|||||..|    |:..|.|..  |.:..|...| ..::...:|.|.:.
plant   178 ------------DVKSSGKRKRGESSLSWDQNMDNSQIFDSHKIDDQTGEVSKIEMPGNSGDIRN 230

  Fly   320 APVSSKADN-SAPAAQDDGSGAPVVRKKAKTKIGNKFKKKNKLKKTKNFPEGEDGEHEHQDYCEV 383
            ..|...:|. :.|......|.|..:|.....:.||....:..|.....|.|.:..:...|....:
plant   231 LHVGLSSDAFTTPQCGWQSSEATAIRPAIHKEPGNNVAGEGFLPSGSPFREQQLKQLRAQCLVFL 295

  Fly   384 CQQGGEIILCDTCPRAYHL-VCLEPELDE---------PPEGKWSCPHCEAD-GGAAE------- 430
            ..:.|.:      |:..|: :.|.....|         .|:|:   .|..:| ||..:
plant   296 ALRNGLV------PKKLHVEIALRNTFREEDGFRGELFDPKGR---THTSSDLGGIPDVSALLSR 351

  Fly   431 --------EEDDDEHQE----------FCRVCKDGGELLCCDSCPSAY--------H---TF--- 463
                    :|.|...:|          |.......|:.|.....||:.        |   ||
plant   352 TDNPTGRLDEMDFSSKETERSRLGEKSFANTVFSDGQKLLASRIPSSQAQTQVAVSHSQLTFSPG 416

  Fly   464 -CLNPPLDTI---------------------------PDGDWR-CPRCSCPP--LTGKAEKII-- 495
             ..|.|.:.:                           .:|:.: .|:.:...  :.|:..|.:
plant   417 LTKNTPSEMVGWTGVIKTNDLSTSAVQLDEFHSSADEEEGNLQPSPKYTMSQKWIMGRQNKRLLV 481

  Fly   496 --TWRWAQRS------------------NDDGPSTSKG--------SKNSNSRVREYFIKWHNMS 532
              :|...|:.                  :||..:.:|.        ..|...|:|..|:  :|
plant   482 DRSWSLKQQKADQAIGSRFNELKESVSLSDDISAKTKSVIELKKLQLLNLQRRLRSEFV--YN-- 542

  Fly   533 YWHCEWVPEVQLDVHHPLMIRSFQRKYDMEEPPKFEESLDEADTRYKRI-QRHKDKVG------M 590
                 :...:..||.|....:..:....:::..|:|:.:.|  .|.:|| :|.|:..|      .
plant   543 -----FFKPIATDVEHLKSYKKHKHGRRIKQLEKYEQKMKE--ERQRRIRERQKEFFGGLEVHKE 600

  Fly   591 KANDDAEVLEER----------FYKNGVKPEWLIVQRVINHRTARD---GSTMYLVKWRELP-YD 641
            |..|..:|..||          |:|   :.|.|       ||...|   ...:.|:|..::. |.
plant   601 KLEDLFKVRRERLKGFNRYAKEFHK---RKERL-------HREKIDKIQREKINLLKINDVEGYL 655

  Fly   642 KSTWEEEGDDI-QGLRQAIDYYQDLRA------VCTS--ETTQSRSKKSKKGRKSKLKVEDDEDR 697
            :...:.:.|.: |.|::...|.|.|.:      :.||  |.....::.|.......|...:||..
plant   656 RMVQDAKSDRVKQLLKETEKYLQKLGSKLKEAKLLTSRFENEADETRTSNATDDETLIENEDESD 720

  Fly   698 PVKHYTPPPEK---PTTDLKKKYEDQPAFLEGTGMQLHPYQIEGINWLRYSWGQGIDTILADEMG 759
            ..|||....||   ....:|:...:||:.|  .|.:|..||:.|:.||...:...::.|||||||
plant   721 QAKHYLESNEKYYLMAHSIKENINEQPSSL--VGGKLREYQMNGLRWLVSLYNNHLNGILADEMG 783

  Fly   760 LGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFELWAPDFYCITYIGDKDSRAVIREN 824
            ||||:|.::.:..|.:..:.||||||.||.|.|..|:.|...|||..:.|.|.|..|.|
plant   784 LGKTVQVISLICYLMETKNDRGPFLVVVPSSVLPGWQSEINFWAPSIHKIVYCGTPDER------ 842

  Fly   825 ELSFEEGAIRGSKVSRLRTTQYKFNVLLTSYELI--SMDAACLGSIDWAVLVVDEAHRLKSNQSK 887
                       .|:.:.:....|||||||:||.:  ..|...|..|.|..:::||.||:|:...|
plant   843 -----------RKLFKEQIVHQKFNVLLTTYEYLMNKHDRPKLSKIHWHYIIIDEGHRIKNASCK 896

  Fly   888 FFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDLQAF--------------QGEFA 938
            ....|..|..:::|||||||||||||||:.|||||..:.||..:.|              ..|.|
plant   897 LNADLKHYVSSHRLLLTGTPLQNNLEELWALLNFLLPNIFNSSEDFSQWFNKPFQSNGESSAEEA 961

  Fly   939 DVSKEEQ---VKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFYKFILTKNYE-A 999
            .:|:||.   :.|||::|.|.:|||||..|...:|.|.|.::|.|.||.||     :|.|..| .
plant   962 LLSEEENLLIINRLHQVLRPFVLRRLKHKVENELPEKIERLIRCEASAYQK-----LLMKRVEDN 1021

  Fly  1000 LNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAGGLYEINSLTKAAGKLVLLSKMLKQ 1064
            |.|.....|.::.|.:|:|:..||||||....:||........: :..:.:..|||.:|.:||.:
plant  1022 LGSIGNAKSRAVHNSVMELRNICNHPYLSQLHSEEVNNIIPKHF-LPPIVRLCGKLEMLDRMLPK 1085

  Fly  1065 LKAQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQEAIDRFNAPGAQQFVFLLST 1129
            |||.:||||.||.||::||::||:|..:.|||.|:||..:|..|...||.||..|:..|:||||.
plant  1086 LKATDHRVLFFSTMTRLLDVMEDYLTLKGYKYLRLDGQTSGGDRGALIDGFNKSGSPFFIFLLSI 1150

  Fly  1130 RAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRK 1194
            ||||:|:||..|||||::|:||||..|:||.:|||||||...|::.||.|.|||||:|...|:.|
plant  1151 RAGGVGVNLQAADTVILFDTDWNPQVDLQAQARAHRIGQKKDVLVLRFETVNSVEEQVRASAEHK 1215

  Fly  1195 MMLTHLVVRPGM--GGKGANFTKQELDDILRFGTEDLFKEDDKEE-AIHYDDKAVAELLDRTNRG 1256
            :.:.:..:..|.  ....|...|:.|:.:||        |..||| |...||.|:.:|:.|....
plant  1216 LGVANQSITAGFFDNNTSAEDRKEYLESLLR--------ESKKEEDAPVLDDDALNDLIARRESE 1272

  Fly  1257 IE------------EKESWANEYL-----SSFKVASYATKEEEEEEETEIIKQDAENSDPAYWVK 1304
            |:            |.|:| |..:     .||............|::.:::.:..:.:|.....|
plant  1273 IDIFESIDKQRKENEMETW-NTLVHGPGSDSFAHIPSIPSRLVTEDDLKLLYETMKLNDVPMVAK 1336

  Fly  1305 ---------------LLRHHYEQHQEDVGRSLGKGKRVRKQVNY----TDGGVVAADTTRDDSNW 1350
                           |..|.|           |:|||.|:..:|    |:........|....:.
plant  1337 ESTVGMKRKDGSMGGLDTHQY-----------GRGKRAREVRSYEEKLTEEEFEKLCQTESPDSP 1390

  Fly  1351 QDNGSEYNSEYSAGSD------EDGGD----------------DDFDDQNGAERKAKRRLER--- 1390
            |..|.  .||.|..:|      |:..|                :....|:...::..:.::|
plant  1391 QGKGE--GSERSLANDTSNIPVENSSDTLLPTSPTQAITVQPMEPVRPQSHTLKEETQPIKRGRG 1453

  Fly  1391 ---RDDRPLPPLLARVGGNIEVLGFNARQRKSFLNAIMRYGMPPQDAFNSQWLVRDLRGKSERNF 1452
               |.|:.|.|:........:..|          |||      ...|....::..|.|.::..:.
plant  1454 RPKRTDKALTPVSLSAVSRTQATG----------NAI------SSAATGLDFVSSDKRLEAASHP 1502

  Fly  1453 KAYVSLFMRHLCEP------GADNAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEH---- 1507
            .:.::|....|..|      .|..|.|...|..| |.||.....|       .::|:...|
plant  1503 TSSLALTSPDLSGPPGFQSLPASPAPTPIRGRGR-GRSRGRGAGR-------GRRVEGVLHGSNS 1559

  Fly  1508 -INGYYSMPELILKPCEPVRSALKQDVAALEAPPTGGNVDKSATTSNSVTPATSAAPSPAPASEK 1571
             |.........:....|..:.||.:..:.:.:.....| :.|.:..:.|:|..||  :.|..|:|
plant  1560 SITQRTETATSLASDAEATKFALPRSASEIVSRVPKAN-EGSTSNPDQVSPVHSA--TTALRSDK 1621

  Fly  1572 GEDKDKDSEKEKDKTSAEKS----EVKQEQEAEEDKK-----------PGDVKQENPVEEAAGDT 1621
            ..|||.|:....|..|..::    |...|::|...||           ||..||...:..:...|
plant  1622 AADKDLDAPPGFDSGSHVQTLNVLENSSERKAFAVKKRPLIQGVSSQHPGPNKQPLDLPVSTSST 1686

  Fly  1622 KPSDAEVKTEVAKTEPKEETKDPEVKEEPKTEEKEKEKVDDKKPIPPTTVIDDDDDDVMIVKEDG 1686
            ......|:.:.|.:...:.:|.|   .|.:|                .|.:    ..|.....|.
plant  1687 LLGGGPVQNQNAVSSVCDGSKSP---SEGRT----------------YTAL----QGVTTAPSDA 1728

  Fly  1687 ELEKPSASSPKDQKAVAAATSAATGATGKGAEDSLEVL------KRKFMFNIADGGFTELHTLWL 1745
            .|  |.:|.|.|  |....:|...|:|.:..|.::..|      ||: :.|:...|.|
plant  1729 TL--PMSSQPSD--ATLPMSSQPVGSTVEAQEANVPSLPAALPAKRR-VRNLPSRGET------- 1781

  Fly  1746 NEEKAAVPGREYEIWHRRHDYWLLAGIVTHGYGRWQDI----QNDIRFAIINEPFKMDVGKGNFL 1806
                   |.|:                   |..|.|.:    .:..|...:..  :::|..||..
plant  1782 -------PKRQ-------------------GKRRGQPLPATDASSARSTGLTP--QIEVKVGNLS 1818

  Fly  1807 EIKNKF--LARRFKLLEQALV--------IEEQLRRAAYLNLAQDPSHPAMSLNARFAEVECLAE 1861
            ..|.||  :|:......|::.        :.:::||        |.|....|...:.|:|..:|.
plant  1819 GTKAKFDAVAKEQPHFSQSVAPDIHSSGSLSQEIRR--------DTSGTGGSARKQTADVTDVAR 1875

  Fly  1862 SHQHL-SKESLAGNK-----------------PANAVLHKVLNQLEELLSDMKS-----DVSRLP 1903
            ..:.: |:.||..:|                 |....||.|.....|..|.:|:     ::|:..
plant  1876 VMKEIFSETSLLKHKVGEPSATTRTNVPDAQSPGEMNLHTVETHKAEDSSGLKNQEALYNLSKAD 1940

  Fly  1904 ATLARIP-PVAQRLQMSERSILSRLAATAGNASN-----------AAQLMAQFPAG--------- 1947
            ..::.|| ||...|            .|:|:.:|           |...:.:.|.|
plant  1941 KLVSDIPHPVPGDL------------TTSGSVANKDVDIGSSKVAAENELVKIPGGDVDSSVIQL 1993

  Fly  1948 FQGTTLPAFTS 1958
            ..|.||.|.:|
plant  1994 SLGNTLTAKSS 2004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357
		TNG2	<282..422	CDD:227367	30/157 (19%)
		PHD1_CHD_II	380..422	CDD:277006	7/51 (14%)
		PHD2_CHD_II	440..482	CDD:277007	12/84 (14%)
		CD1_tandem_CHD3-4_like	487..557	CDD:349314	15/99 (15%)
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	12/58 (21%)
		PLN03142	720..>1234	CDD:215601	216/535 (40%)
		DUF1087	<1292..1334	CDD:461922	11/60 (18%)
		CHDII_SANT-like	1380..1517	CDD:461920	27/153 (18%)
		CHDCT2	1757..1902	CDD:462358	32/181 (18%)
SYD	NP_001325348.1	QLQ	277..310	CDD:214931	6/38 (16%)
		PLN03142	604..>1216	CDD:215601	241/646 (37%)
		SnAC	1282..1369	CDD:464219	17/98 (17%)
		PHA03307	1491..>1819	CDD:223039	79/401 (20%)
		rne	<3168..3342	CDD:236766