Protein Alignment Mi-2 and CHR5

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_178970.3
• Gene: CHR5 / 815823
• AraportID: AT2G13370
• Length: 1724
• Species: Arabidopsis thaliana
• Alignment Length: 2029
• Identity: 540/2029 - (26%)
• Similarity: 840/2029 - (41%)
• Gaps: 545/2029 - (26%)

  Fly     5 EENDDNFQE-------EEEAQEDNAPAAELSNDSDAPLKPNQNDEDDDYDPEDSRRKKKGKK--- 59
            |:.|..:.|       :.:.|.|..|...:.       :||:...|:..||.||..:...|:
plant    36 EDVDGTYSERGFDMNMDVQYQSDPEPGCSIR-------QPNETAVDNVADPVDSHYQSSTKRLGV 93

  Fly    60 --------------RKTRKGEEKGRKKKKRKKNESEEDSDFVQHDEEVEYPSTSKRGRKRKEEKQ 110
                          ...|:|.:..:..:...| |:....|...:|...:..|.::...:.:||..
plant    94 TGRWGSTFWKDCQPMGQREGSDPAKDSQSGYK-EAYHSEDNHSNDRSEKLDSENENDNENEEEDN 157

  Fly   111 AAKEKESASSGMPSVEDVCSAFSVCNVEIEYSEEELQSLTTYKAFMHHVRPILQKENPK----IA 171
            ...:.:|..:.:|:.|.:..         ||.|::..:.:.:..:..:..|...:..||    :.
plant   158 EMNKHQSGQADVPADEMLSD---------EYYEQDEDNQSDHVHYKGYSNPTNSRSLPKAGSAVH 213

  Fly   172 APKLVMLVAAKWREFCESN---------PHIQQEG------------GAAGSGGSA---GQARSV 212
            :.........|...:.:||         .:.::|.            .||..||::   ||...|
plant   214 SNSRTSRAIHKNIHYSDSNHDHNGDADMDYEEEEDEDDPEDADFEPYDAADDGGASKKHGQGWDV 278

  Fly   213 TGDEPEEPRSSRSSRNEKPDDIYEEAVEEEEEEEEEEKKPRRKRSGRGKKGRRPSGKVPTLKIKL 277
            :.::||..               ||....:.|::...|||:.::..:|  .|:.|..:......:
plant   279 SDEDPESD---------------EEIDLSDYEDDYGTKKPKVRQQSKG--FRKSSAGLERKSFHV 326

  Fly   278 LGKRKRDSSDEEQDASGASERDSDLEFERMLQKSDDSADEKEAPVSSKADNSAPAAQDDGSGAPV 342
            ..::||.:|.::.|:...||.|:|..|.                  |.|.......|::|.....
plant   327 SSRQKRKTSYQDDDSEEDSENDNDEGFR------------------SLARRGTTLRQNNGRSTNT 373

  Fly   343 VRKKAKTKIGNKFKKKNKLKKTKNFPEGEDGEHEHQDYCEVCQQGGEIILCDTCPRAYHLVCLEP 407
            :.:.::.:...:..:|      .::.|.||.|
plant   374 IGQSSEVRSSTRSVRK------VSYVESEDSE--------------------------------- 399

  Fly   408 ELDEPPEGKWSCPHCEADGGAAEEEDDDEHQEFCRVCKDGGELLCCDSCPSAYHTFCLNPPLDTI 472
            ::|              ||...:.:.||..:|
plant   400 DID--------------DGKNRKNQKDDIEEE--------------------------------- 417

  Fly   473 PDGDWRCPRCSCPPLTGKAEKIITWRWAQRSNDDGPSTSKGS----------KNSNSRVREYFIK 527
             |.|             ..||:: |...:...:|..:.:|.:          ...:....|:.||
plant   418 -DAD-------------VIEKVL-WHQLKGMGEDVQTNNKSTVPVLVSQLFDTEPDWNEMEFLIK 467

  Fly   528 WHNMSYWHCEWVPEVQLDVHHPLMIRSFQRKYDMEEPPKFEESLD-----EADTRYKRIQRHKDK 587
            |...|:.||:|                 :...|::....|::.|:     ..:.||:.....::
plant   468 WKGQSHLHCQW-----------------KTLSDLQNLSGFKKVLNYTKKVTEEIRYRTALSREE- 514

  Fly   588 VGMKANDDAEVLEERFYKNGVKPEWLIVQRVINHRTARDG----STMYLVKWRELPYDKSTWEEE 648
              ::.||.::.::....|...:     |:|:|..|.::||    ...|||||:.|.|.::|||::
plant   515 --IEVNDVSKEMDLDIIKQNSQ-----VERIIADRISKDGLGDVVPEYLVKWQGLSYAEATWEKD 572

  Fly   649 GDDIQGLRQAIDYYQDLRAVCTSETTQSRSKKSKKGRKSKLKVEDDEDRPVKHYTPPPEKPTTDL 713
             .||...:.|||.|: .|.|..:...:...::..||:.|
plant   573 -VDIAFAQVAIDEYK-AREVSIAVQGKMVEQQRTKGKAS-------------------------- 609

  Fly   714 KKKYEDQPAFLEGTGMQLHPYQIEGINWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSLYKEGH 778
            .:|.::||.:|  .|..|..||:||:|:|..||....:.|||||||||||:|:|:.|..|.....
plant   610 LRKLDEQPEWL--IGGTLRDYQLEGLNFLVNSWLNDTNVILADEMGLGKTVQSVSMLGFLQNTQQ 672

  Fly   779 CRGPFLVAVPLSTLVNWEREFELWAPDFYCITYIGDKDSRAVIRENELSFEEGAIRGSKVSRLRT 843
            ..|||||.||||||.||.:||..|.|....|.|:|.:.||.|.::.|...|:      ||.|
plant   673 IPGPFLVVVPLSTLANWAKEFRKWLPGMNIIVYVGTRASREVCQQYEFYNEK------KVGR--- 728

  Fly   844 TQYKFNVLLTSYELISMDAACLGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPL 908
             ..|||.|||:||::..|.|.|..|.|..|:||||||||:::::.:..|..::...|||:|||||
plant   729 -PIKFNALLTTYEVVLKDKAVLSKIKWIYLMVDEAHRLKNSEAQLYTALLEFSTKNKLLITGTPL 792

  Fly   909 QNNLEELFHLLNFLSRDKFNDLQAFQGEFADVS--KEEQVKRLHEMLGPHMLRRLKTDVLKNMPS 971
            ||::|||:.||:||...||.:...|...:.::|  .|.::..||..|.||:|||:..||.|::|.
plant   793 QNSVEELWALLHFLDPGKFKNKDEFVENYKNLSSFNESELANLHLELRPHILRRVIKDVEKSLPP 857

  Fly   972 KSEFIVRVELSAMQKKFYKFILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEAT 1036
            |.|.|:|||:|.:||::||:||.:|:..||....|...||:||:::||||||||:||    |.|.
plant   858 KIERILRVEMSPLQKQYYKWILERNFHDLNKGVRGNQVSLLNIVVELKKCCNHPFLF----ESAD 918

  Fly  1037 TAAGGLYEINSLTK------AAGKLVLLSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQYK 1095
            ...||  :||..:|      ::||||:|.|:|.:|:...|||||||||.:|||||.::|....::
plant   919 HGYGG--DINDNSKLDKIILSSGKLVILDKLLVRLRETKHRVLIFSQMVRMLDILAEYLSLRGFQ 981

  Fly  1096 YERIDGGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAF 1160
            ::|:||.....|||:|:|.||||.:..|.||||||||||||||||||||:|:||||||.||:||.
plant   982 FQRLDGSTKAELRQQAMDHFNAPASDDFCFLLSTRAGGLGINLATADTVVIFDSDWNPQNDLQAM 1046

  Fly  1161 SRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRP-GMGG--------KGANFTKQ 1216
            ||||||||...|.||||||..||||.:.:.|||||:|.|||::. ...|        ||:||.|.
plant  1047 SRAHRIGQQEVVNIYRFVTSKSVEEEILERAKRKMVLDHLVIQKLNAEGRLEKRETKKGSNFDKN 1111

  Fly  1217 ELDDILRFGTEDLFKED--DKEEAIHYDDKAVAELLDRTNRGIEEK--ESWANEYLSSFKVASYA 1277
            ||..|||||.|:|||||  |:|.........:.|:|:|..: :|||  :...:|.|.:||||::.
plant  1112 ELSAILRFGAEELFKEDKNDEESKKRLLSMDIDEILERAEQ-VEEKHTDETEHELLGAFKVANFC 1175

  Fly  1278 TKEEEEEEETEIIKQDAENSDPAYWVKLLRHHYEQHQEDVGRSLGKGKRVRKQVNYTDGGVVAAD 1342
            ..|:                |.::|.:.::.......|:   :|.. :..|...:|.|..  ..|
plant  1176 NAED----------------DGSFWSRWIKPDSVVTAEE---ALAP-RAARNTKSYVDPS--HPD 1218

  Fly  1343 TTRDDSNWQDNGSEYNSEYSAGSDEDGGDDDFDDQNGAERKAKRRLERRDDRPLPPLLARVGGNI 1407
            .|   |..:..|||                   .....||..||| :.....|..|||.  |.:.
plant  1219 RT---SKRKKKGSE-------------------PPEHTERSQKRR-KTEYFVPSTPLLE--GTSA 1258

  Fly  1408 EVLGFN-----ARQRKSFLNAIMRYGMPPQDAFNSQWLVRDLRGKSERNFKAYVSLFMRHL--C- 1464
            :|.|::     .|..:.|...:|::|...|.|..::.:...:....|   :|.|.||...:  |
plant  1259 QVRGWSYGNLPKRDAQRFYRTVMKFGNHNQMACIAEEVGGVVEAAPE---EAQVELFDALIDGCK 1320

  Fly  1465 --------EPGADNAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEF-EHINGY----YSMPE 1516
                    ||.....:.|  |||   :....:|.|:..:.|:.|::..: :.|:.:    |..|.
plant  1321 ESVETGNFEPKGPVLDFF--GVP---VKANELLKRVQGLQLLSKRISRYNDPISQFRVLSYLKPS 1380

  Fly  1517 LILKPC----------------------EPVR----SALKQDVAALEAP------PTGGNVDKSA 1549
            ...|.|                      |.:|    ..|.:.:|.:|..      |...|:.:.|
plant  1381 NWSKGCGWNQIDDARLLLGILYHGFGNWEKIRLDESLGLTKKIAPVELQHHETFLPRAPNLKERA 1445

  Fly  1550 TTSNSVTPATSAAPSP-APASEKGEDKDKDSEKEKDKTSAEKSEVKQEQEAEEDKKPGDVKQENP 1613
            |....:..|.:...:. |.||.|...|.||:...:.|..|.....|                ..|
plant  1446 TALLEMELAAAGGKNTNAKASRKNSKKVKDNLINQFKAPARDRRGK----------------SGP 1494

  Fly  1614 VEEAAGDTKPSDAEVKTEVAKTEPKEE---TKDPEVKEEPKTEEKEKEKVDDKKPIPPTTVIDDD 1675
            ...:...||  |...||:.|:...|||   :.|.||.|:.| |:|..|..:|        |:.|:
plant  1495 ANVSLLSTK--DGPRKTQKAEPLVKEEGEMSDDGEVYEQFK-EQKWMEWCED--------VLADE 1548

  Fly  1676 DDDVMIVKEDGELEKPSASSPKDQKAVAAATSAATGATGKGAEDSLEVLKRKFMFNIADGGFTEL 1740
                  :|..|.|::            ...|||             ::.|.|.:|.|
plant  1549 ------IKTLGRLQR------------LQTTSA-------------DLPKEKVLFKI-------- 1574

  Fly  1741 HTLWLNEEKAAVPGREY-EIWHRRHDYWLLAGIVTHGYGRWQDIQNDIRFAIINEPFKMDVGKGN 1804
                          |.| ||..||.|    |.::.|.    :|:....|         |.:...|
plant  1575 --------------RRYLEILGRRID----AIVLEHE----EDLYKQDR---------MTMRLWN 1608

  Fly  1805 FLEIKNKFLARRFKLLEQALVIEEQLRRAAYLNLAQDPSHPAMSLNARFAEVECLAESHQHLSKE 1869
            ::...:.....|...:...|..|::.....      .|||    ||.        :.:.|...|.
plant  1609 YVSTFSNLSGDRLNQIYSKLKQEKEEEEGV------GPSH----LNG--------SRNFQRQQKF 1655

  Fly  1870 SLAGNKPANAVLHK 1883
            ..|||...:..:||
plant  1656 KTAGNSQGSQQVHK 1669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357	9/65 (14%)
		TNG2	<282..422	CDD:227367	19/139 (14%)
		PHD1_CHD_II	380..422	CDD:277006	1/41 (2%)
		PHD2_CHD_II	440..482	CDD:277007	2/41 (5%)
		CD1_tandem_CHD3-4_like	487..557	CDD:349314	13/79 (16%)
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	22/57 (39%)
		PLN03142	720..>1234	CDD:215601	265/532 (50%)
		DUF1087	<1292..1334	CDD:461922	5/41 (12%)
		CHDII_SANT-like	1380..1517	CDD:461920	37/157 (24%)
		CHDCT2	1757..1902	CDD:462358	27/128 (21%)
CHR5	NP_178970.3	MSCRAMM_ClfA	<106..420	CDD:468110	65/445 (15%)
		CD1_tandem	418..498	CDD:349307	18/110 (16%)
		CD2_tandem	531..587	CDD:349306	22/62 (35%)
		PLN03142	612..>1152	CDD:215601	271/557 (49%)
		DUF4208	1534..1626	CDD:464035	30/169 (18%)