Protein Alignment Mi-2 and smarcal1

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_073768103.1
• Gene: smarcal1 / 560412
• ZFINID: ZDB-GENE-041210-303
• Length: 810
• Species: Danio rerio
• Alignment Length: 674
• Identity: 158/674 - (23%)
• Similarity: 263/674 - (39%)
• Gaps: 154/674 - (22%)

  Fly   645 WEEEGDDIQG---------LRQAIDYYQDLRAVCTSETTQSRSKKSKKGRKSKLKVED------- 693
            |::.|..|:|         |...|.|..|:..:.....::|...|:   ||....:||
Zfish   231 WQKPGATIKGKCVLVSRSRLEVDIGYQADVIGIFKQMPSKSYDMKT---RKWTFLLEDYGKLMAD 292

  Fly   694 ------DEDRPVKH-------------YTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQIEGI 739
                  .|..|:.|             .:..|..|..||.   ...|....    .|.|:|.:|:
Zfish   293 LNELPTVETEPLPHAVLQSFSSQFEKTESRAPVPPEADLS---HIDPQLTR----SLMPFQRDGV 350

  Fly   740 NWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFELWAP 804
            |:.....|:   .:|||:||||||:|.:. :.:.|:.   ..|.||..|.|....|...|..|.|
Zfish   351 NFAVSREGR---LLLADDMGLGKTVQAIC-IAAYYRS---EWPLLVVAPSSVRFTWAEAFRRWLP 408

  Fly   805 DFYCITYIGDKDSRAVIRENELSFEEGAIRGSKVSRLRTTQYKFNVLLTSYELISMDAACLGSID 869
            ..       ..||..|:.:.:.:...|.|               |::  ||:|::.......|..
Zfish   409 SV-------KPDSINVVVKGKDNLRSGLI---------------NII--SYDLLNKMDKQPPSSP 449

  Fly   870 WAVLVVDEAHRLKSNQSKFFR----ILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDL 930
            :.|:::||:|.||:.::...|    :|.  |....:||:|||..:...||:..:..:....|...
Zfish   450 FNVIIMDESHFLKNMKTARCRAALPLLK--TAKRVILLSGTPAMSRPAELYTQIQAVRPALFPRF 512

  Fly   931 QAFQGEFADVSK-------------EEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELS 982
            ..|...:.|..:             .|....|.|.|   ||||||::||..:|:|
Zfish   513 HDFGTRYCDAKQLPWGWDYSSSSNLTELKLLLEESL---MLRRLKSEVLSQLPAK---------- 564

  Fly   983 AMQKKFYKFILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAGGLYEINS 1047
              |:|    ::|...:.:||::   ..:|.....:|.|    .|...|..:||.     |...|.
Zfish   565 --QRK----VVTVTTDGINSRT---KAALNAAARELAK----GYHNKSQEKEAL-----LVFFNH 611

  Fly  1048 LTKAAGKLVL--LSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQE 1110
            ..:|..:.::  :|.|   |:....:.|:|:....:||.:...|..:...:.||||......||.
Zfish   612 TAEAKIRAIMEYISDM---LECGREKFLVFAHHKLVLDSITKELGEKSISFIRIDGSTPSAERQL 673

  Fly  1111 AIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIY 1175
            ..:||.| ..|..|.:||..|..:|:.|.:|..|:..:..|||...|||..|.|||||.:.|.|:
Zfish   674 LCERFQA-SQQSCVAVLSITAANMGLTLHSAALVVFAELFWNPGVLIQAEDRVHRIGQTSNVDIH 737

  Fly  1176 RFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRFGTEDLFKEDDKEEAIH 1240
            ..|.:.:.::.:..:.:.||   :::.:.|:                   :|....|:.:..:.|
Zfish   738 YLVAKGTADDYLWPMIQAKM---NVLEQVGL-------------------SESNISENAESASFH 780

  Fly  1241 YDDKAVAELLDRTNRGIEEKESWA 1264
            ..|:....:.:...|..:|.|..|
Zfish   781 SRDRQQLTITEMFQRSFDEDEMLA 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357
		TNG2	<282..422	CDD:227367
		PHD1_CHD_II	380..422	CDD:277006
		PHD2_CHD_II	440..482	CDD:277007
		CD1_tandem_CHD3-4_like	487..557	CDD:349314
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	7/27 (26%)
		PLN03142	720..>1234	CDD:215601	131/532 (25%)
		DUF1087	<1292..1334	CDD:461922
		CHDII_SANT-like	1380..1517	CDD:461920
		CHDCT2	1757..1902	CDD:462358
smarcal1	XP_073768103.1	None